Optimum water and nutrient coupling are the primary requirements for sustainable plant production. A field experiment designed with three tiers of irrigation i.e., I0: rainfed, I1: 1.0 crop evapotranspiration (1.0 ) and I2: 0.75 and four tiers of nutrition i.e., N0: control (no manure and fertilizer), N1: 100% recommended dose of fertilizer (RDF) as FYM, N2: 50% RDF as FYM + 50% RDF as chemical fertilizers and N3: 100% RDF as chemical fertilizers was conducted for four consecutive years (2015-2018) on large cardamom in a hilly terrain of sub-Himalayan region in India. The results showed that microsprinkler irrigation at 1.0 along with full dose of chemical fertilizers (20:40:40::N:P2O5:K2O kg ha-1) recorded the highest growth, yield attributes, fresh (665.22 kg ha-1) and dry (282.03 kg ha-1) capsule yields, the greatest water use efficiency (0.18 kg ha-1 mm-1) and the largest soil availability and plant leaf accumulation of N, P and K. The soil water contents increased with incremental soil depth and irrigation regime, and continued to rise up to flowering stage, sharply dropped at capsule development stage and further increased at maturity stage. The predictive regressive models showed the linear relationships between the dry capsule yield and irrigation water and total water use.