Status of Acute Symptomatic Seizures in a Female Patient with Thyrotoxicosis: Hashimoto’s Encephalopathy. A Case Report

Tokareva, Yu. V.; Котов, А. С.; Семенова, Екатерина Юрьевна; Eliseev, Yu. V.; Романова, М. В.; Alakova, M. A.; Мисникова, И. В.; Komerdus, Irina

doi:10.1134/s0362119717080138

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“…Diagnosis of HE should be considered in patients presenting with the neuropsychiatric symptoms and high levels of thyroid antibodies in serum or CSF, in particular thyroperoxidase antibodies excluding other causes of encephalopathy, such as the central nervous system involvement of vasculitic syndromes, metabolic disease, electrolyte imbalance, intracranial infection, poisoning or toxins, and neoplasm. 1,3,4,13,14 EEG abnormalities presented were nonspecific in majority of patients with slow background diffusion. 2,3,10,14 Brain MRI may show abnormalities such as cerebral atrophy, focal cortical abnormality, diffuse subcortical abnormality and nonspecific subcortical focal white matter abnormality.…”

Section: Discussionmentioning

confidence: 93%

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A case report on Hashimoto’s encephalopathy: an autoimmune neuroendocrine disorder

et al. 2020

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Hashimoto’s encephalopathy (HE) is a rare neuroendocrine disorder with high titers of the thyroid antibodies. HE is more common to women than in men with a ratio of approximately 5:1. The estimated prevalence of HE was 2 per 100,000 people. We present a case of Hashimoto’s encephalopathy in a 24-year-old male patient known case of hypothyroidism admitted with the complaints of unconsciousness, and further developed seizure during admission. Brain magnetic resonance imaging (MRI) was normal, electroencephalogram (EEG) revealed slow diffusion, and the serum thyroid function test showed a high concentration of anti-thyroid antibodies. The patient had a good recovery after the management with steroid therapy.

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Section: Discussionmentioning

confidence: 93%

“…3 First described by the famous British neurologist L. Brain in 1966. 4 HE is more common to women than in men with a ratio of approximately 5:1 and occurs in all age groups. The estimated prevalence of HE was 2 per 100,000 people.…”

Section: Introductionmentioning

confidence: 99%