Status of Bacteriophage Genetic Modifications: a Review

Abstract

Engineering is the branch that covers many areas leading to a discipline termed as synthetic biology. The researchers made possible engineering at genetic level of bacteriophages which are well known for killing bacteria although they develop resistance against bacteriophages resulting into challenges in disease control programs. The genetic alterations give new characters to the phage which may be helpful to bring vital changes in phage science. In this review, we have investigated the genetic modification of bacteriophages with its applications.