Status of bone health and association of socio-demographic characteristics with Bone Mineral Density in Pakistani Females

Tariq, Saba; Baig, Mukhtiar; Tariq, Sundus; Shahzad, Muhammad

doi:10.12669/pjms.35.3.551

Cited by 14 publications

(16 citation statements)

References 20 publications

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“…In our results, 145 females were examined by DEXA scan, of whom (55.17%) were diagnosed as abnormal bone mineral density and (44.83%) were with normal bone mineral density results. This is in accordance with other studies in Saudi, Syrian and Iranian women, [23][24][25][26]. While this is in discordance with Brazilian study, 36.5% of women had normal BMD, and 63.5% were diagnosed with abnormal BMD [27].…”

Section: Discussionsupporting

confidence: 91%

Association of Anti-Mullerian Hormone and 25-Hydroxyvitamin D in women with low bone mineral density in Babylon, Iraq

Saffar¹,

Taee²

2020

ATMPH

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Background: Decrease Anti-mullerian hormone and vitamin D was linked to increased risks of osteopenia and osteoporosis. Aim of the study: To find any association of Anti-Mullerian hormone and 25-hydroxyvitamin D serum levelswith bone minerals density test results in women. Material and Methods: The study was design as a cross-sectional; it includes one hundred forty five females, their age range from 23-68 years. These females attended Rheumatology department of Merjan Medical City in Babylon /Iraq through the period from September 2017 till March 2018.Hormonal profile (anti-mullarian hormone, and vitamin D) were assessed; and minerals density of the bone was measured by dualenergy x-ray absorptiometry for all participants. Results:The incidenceof osteoporosis and osteopenia in our studied population was(31, 72%, 23.45%) respectively and (44.83%) were with normal resultof bone mineral density study. Significant positivecorrelation (p<0.05) was found between Anti-Mullerian Hormone and Vitamin D serum concentrations with bone minerals densitystudy results. Conclusions:Vitamin D serum levels significantly correlates with Anti-mullerian serum levels in patients withabnormal bone mineral density.

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Section: Discussionsupporting

confidence: 91%

Association of Anti-Mullerian Hormone and 25-Hydroxyvitamin D in women with low bone mineral density in Babylon, Iraq

Saffar¹,

Taee²

2020

ATMPH

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“…Therefore, it is important to find new diagnostic and therapeutic targets to treat this disease effectively. 17 In this study, we found that serum chemerin was increased in the osteoporotic group compared to normal control, indicating that serum chemerin might be involved in osteoporosis's pathogenesis. Similar to our results, another study reported an increased level of serum chemerin in patients with osteoporosis.…”

Section: Discussionmentioning

confidence: 51%

Association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal females

Tariq

Tariq²,

Shahzad³

2021

Pak J Med Sci

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Objectives: To investigate the association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal non-osteoporotic and osteoporotic females. Methods: This cross-section analysis was carried out at the orthopedic department of Madina Teaching Hospital, Faisalabad, Pakistan, in the year 2017-2019. Postmenopausal females were divided into two groups according to their bone mineral density (BMD). All osteoporotic females had a T-score of -2.5 or less. Data were analyzed on SPSS-24. Results: A total of 140 women were included in our study (80 osteoporotic and 60 non-osteoporotic). Non significant difference in age and BMI was observed between osteoporotic and non-osteoporotic subjects (p=0.152) and (p=0.291) respectively. There was a significant difference found in total BMD, serum chemerin levels between osteoporotic and non-osteoporotic subjects p<0.001 in both parameters. No significant correlation of serum chemerin was found with serum calcium, serum alkaline phosphatase and BMD in postmenopausal osteoporotic females (p=0.907), (p=0.318) (p=0.664) respectively. A significant negative correlation was found between serum alkaline phosphatase levels and total BMD in postmenopausal osteoporotic females (p=- 0.039). Linear regression analysis of serum alkaline phosphatase levels with total BMD showed no association between BMD and serum alkaline phosphatase levels (p=0.869). Conclusion: There is no association of serum chemerin with calcium, ALP and bone mineral density in non-osteoporotic and osteoporotic postmenopausal females. doi: https://doi.org/10.12669/pjms.37.2.3907 How to cite this:Tariq S, Tariq S, Shahzad M. Association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal females. Pak J Med Sci. 2021;37(2):---------. doi: https://doi.org/10.12669/pjms.37.2.3907 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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“…Whereas Tariq S et al [16] found no significant difference in BMD of both rural and urban areas (p=0.321). Of the 350 patients 119 said their physical activity was low i.e.…”

Section: Pareek Et Al; Proportion Of Radiologically Confirmed Osteoporosis Casesmentioning

confidence: 86%

Assessment of Proportion of Radiologically Confirmed Osteoporosis Cases among the Suspected Cases of Female: An Institutional Based Study

Pareek¹,

Agarwal²,

Mathur³

2019

AJMR

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Background: Preventing osteoporosis, a multi factorial disease, resides not only in recognizing its risk factors, but also in identifying potentially modifiable determinants of bone mineral density (BMD), the surrogate measure for osteoporosis. Thus, the present study is designed to assess and compare the risk factors of osteoporosis among women as to prevent osteoporosis, a multi factorial disease, resides not only in recognizing its risk factors, but also in identifying potentially modifiable determinants of bone mineral density (BMD), the surrogate measure for osteoporosis. Subjects and Methods: The present prospective observational analytical study was commenced among 350 females aged between 30-65years who were referred to the Radio diagnosis department as suspected cases of osteoporosis from various outpatient departments. Women in sample after DEXA scan were categorized in two groups; group A comprised women those having normal BMD, considered as control group and group B comprised women with low BMD either osteopenia or osteoporosis included in this group. Datawas collected according to the recommendations of the International Society for Clinical Densitometry.The data collected was compiled, tabulated, analyzed and subjected to Pearson Chi-square test for statistical analysis. Results: While osteoporosis was found to be significantly higher in Low class women (p<0.07) followed by Middle class and upper socioeconomic status. A significant difference was observed between rural and urban people (p<0.01). Women with moderate and low physical activity were significantly at higher risk of osteoporosis. A highly significant difference was observed between two groups in terms of weight, age, BMI, Waist circumference, Hip circumference, BMD lumbar spine, Lumbar Spine T score, Lumbar spine Z score, Femur neck BMD, Femur neck T score & Femur neck Z score whereas there was no significant difference in terms of Height. Conclusion: Within the limits of our study we conclude that osteoporosis is one of the growing concern and need immediate care. The lack of information regarding risk factors for osteoporosis among women is an important problem. Our results highlight the importance of knowledge regarding the risk factors like age, menopausal status, physical activity, smoking, socioeconomic status, geographical location, weight, BMI etc. There is the need for more effective education for the community and medical practitioners for the clinical significance of osteoporotic fractures and its risk factors.

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Status of bone health and association of socio-demographic characteristics with Bone Mineral Density in Pakistani Females

Cited by 14 publications

References 20 publications

Association of Anti-Mullerian Hormone and 25-Hydroxyvitamin D in women with low bone mineral density in Babylon, Iraq

Association of Anti-Mullerian Hormone and 25-Hydroxyvitamin D in women with low bone mineral density in Babylon, Iraq

Association of serum chemerin with calcium, alkaline phosphatase and bone mineral density in postmenopausal females

Assessment of Proportion of Radiologically Confirmed Osteoporosis Cases among the Suspected Cases of Female: An Institutional Based Study

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