Status of the Project of Radioisotope Complex Ric-80 (Radioisotopes at Cyclotron C-80) at Pnpi

Abstract

Abstract. Presently, the cyclotrons are playing a very important role in the production of radionuclides for medicine, which are very safe and reliable installations. From radioisotopes produced with cyclotrons, it is rather easy to select one that has appropriate nuclear-physical characteristics for medical use, in comparison to the ones produced with reactors. At PNPI, a high current cyclotron C-80 with the energy of extracted proton beam of 40-80 MeV and the current up to 200 µA is under construction. One of the main goals of C-80 is the production of a wide spectrum of medical radionuclides for diagnostics and therapy. At present time, a project is worked out for the construction of radioisotope complex RIC-80 (Radioisotopes at the cyclotron C-80) at the beam of C-80. In the presented submission, the project of RIC-80 complex is discussed, which includes three target stations for the production of a large set of radionuclides for medicine. The peculiarity of the proposed radioisotope facility is the use of the mass-separator with the target-ion source device as one of the target stations for on-line, or semi on-line production of a high purity separated radioisotopes. The first results on the target development for production of different medical radionuclides, including radioisotope generator for PET diagnostics 82 Sr, are presented as well.

NEW METHOD DEVELOPMENT FOR MEDICAL RADIONUCLIDE 223,224Ra, 225Ac PRODUCTION

“…The measured cross-sections of 227 Th and 225 Ac production from a thorium target by the 80 MeV protons are 30 and 5 mb, respectively [7]. A high-temperature method of extraction of 223,224 Ra produced by protons in 238 UC was described in detail in [8]. In Fig.…”

“…Figure1. Alpha spectrum of species evaporated at 2400°C from a UC target on the cooled tantalum collector[8] …”

Target Development for Medical Radionuclides Cu-67 and Sr-82 Production

“…Concerning the efficiency of the RbCl target material evaporation, the weighting procedure gives the value better 99.9% and gamma-spectrometry analysis (integral counts of the peak before/after heating) with the background subtraction gives of about 99% concerning the measurement errors). Finally remaining radioactive Sr atoms can be evaporated from the vessel at higher temperature [6], or washed by a small amount of an acid solution. Count EkeV Figure 3.…”

“…The spectrum of the vessel with the irradiated RbCl after heating at the temperature up to 500 °C is shown with red circles. The spectrum at the collector after one-hour vessel heating at the temperature of 1900-1950 °C [6] is shown with green triangles. The vessel is shown after one hour-heating at the temperature of 900 °C.…”

“…After that, strontium was selectively extracted by washing the internal vessel volume with HCl solution. Another way of strontium extraction was the niobium or tantalum vessel use, heating it up to 1900°C [6] after the target material evaporation at 900 °C. The evaporated strontium atoms were directed to the collector cooled by the floating water.…”