Status of Using Probiotic Supplementation in Acne

Hattiholi, Aishwarya; Tendulkar, Shivani; Dodamani, Suneel

doi:10.1007/978-981-16-5628-6_6

Cited by 1 publication

(1 citation statement)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[9–12] The administration of probiotics has proven beneficial when addressing antibiotic resistance and inhibiting inflammation in serious cases. [ 13 ] However, the application of live bacteria on the skin poses several challenges,[ 14 ] and skincare products containing probiotics are generally illegal in China. The term “postbiotics” was defined as the “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host” by the International Scientific Association of Probiotics and Prebiotics in 2019.…”

Section: Introductionmentioning

confidence: 99%

Development of Novel Topical Anti-Acne Cream Containing Postbiotics for Mild-to-Moderate Acne

Cui¹,

Feng²,

Guo³

et al. 2022

Indian Journal of Dermatology

View full text Add to dashboard Cite

Background: Acne is one of the most common skin diseases in adolescents and results in high healthcare costs and psychological burdens severely affecting individuals. Treatments other than contraceptives, antibiotics, and photodynamic therapies are needed to prevent and/or improve acne's onset and evolution. Aims: The purpose of this study was to investigate the efficacy of a fermentation lysate of Lactiplantibacillus plantarum VHProbi® V22 in ameliorating acne. Methods: An anti-acne skincare cream containing fermentation culture lysate was applied to subjects with mild-to-moderate acne vulgaris for 4 weeks. The assessments were evaluated based on instrumental measurements using Visia®-CR and CK-MPA® systems. Results and Conclusions: The anti-acne skincare cream was found to be safe and not cause any irritation. Significant improvements in the acne lesion proportion (P < 0.01), transepidermal water loss (P < 0.001), and sebum secretion (P < 0.05) were observed in comparison to the baseline in the subjects. The analysis of the statistical data after 4 weeks of treatment showed a positive decrease in skin tone, stratum corneum hydration, and superficial pH without statistical significance, compared with the baseline. The results of this study suggest that the topical application of the anti-acne skincare cream was effective and safe in subjects with mild-to-moderate acne and could represent an optional complement for acne treatments.

show abstract

Section: Introductionmentioning

confidence: 99%