Statut de la vitamine D chez les patients diabétiques de type 2 marocains

Safi, S.; Ouleghzal, H.; Khaldouni, I.; Hassikou, H.; Ballouch, L; Bamou, Youssef; Hadri, L.

doi:10.1016/s1957-2557(15)30018-3

Cited by 6 publications

(9 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vitamin D deficiency is widespread worldwide including in countries with significant sunlight. This is a public health problem emerging [2].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have reported an association between vitamin D status and the development of type 2 diabetes. Vitamin D deficiency decreases insulin sensitivity, glucose tolerance and beta-pancreatic function [2].…”

Section: Discussionmentioning

confidence: 99%

“…In our series, the mean value of 25 (OH) vitamin D3 was 12.55 ± 8.14 ng / ml; 95.2% of our patients had a deficiency or deficiency of Vitamin D. Our results are consistent with the 25 (OH) D levels found in other studies. A study carried out at the Moulay Ismail Hospital in Meknes (Morocco) in 2015 showed that the average concentration of 25 (OH) D in diabetic patients was 10.95 ± 6.99 ng / ml, with a prevalence of Vitamin D deficiency of 98.1% [2]. Nobécourt et al, [8] had in a French population composed of 638 diabetic patients, vitamin D deficiency (< 30 ng / ml) in 93% of cases, and severe (< 10 ng / ml) in 20% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the correlation between vitamin D status and glycemic control, the different treatments for diabetes and these degenerative complications, Suzuki et al [2,13], in a Japanese study of T2D patients with a mean duration of diabetes of 12 years, found a negative correlation between the levels of Vitamin D and HbA1c, proliferative diabetic retinopathy, and the type of treatment (insulin) as well as the number of microvascular complications.…”

Section: Discussionmentioning

confidence: 99%

“…The progression of the fundamental and clinical knowledge made it possible to conclude to its implication in the pathogenesis of insulin-resistance in the event of deficiency [1]. This insulin resistance is a major risk factor for diabetes contributing to its pathogenesis and decreased glucose tolerance [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Type 2 Diabetes and Vitamin D Status

Meriem¹,

Tali²,

Hanane³

et al. 2019

AJLM

View full text Add to dashboard Cite

Vitamin D (Vitamine D), classically recognized as an important player in bone and phosphocalcic metabolism, has shown, through recent studies, its involvement in the pathogenesis of insulin resistance in case of deficiency. The aim of this work is to describe the profile of vitamin D in a type 2 diabetic population and to correlate the vitamin D status with the different metabolic parameters in this population admitted in the University Hospital of Marrakech. It is a descriptive crosssectional study of a population of type 2 diabetic patients, coming for a follow-up assessment of diabetes and having performed an evaluation of the level of 25 hydroxy vitamin D3 in blood. Demographic, clinical, evolutionary and biological data were collected. The mean of 25 (OH) vitamin D3 was 12.55 ± 8.14 ng / ml for the group, and was 13.15 ± 8.93 ng / ml for women and 11.82 ± 7.31 ng / ml for men. These patients were classified into three groups: Group 1: 25 (OH) D < 10 ng / ml objectified in 37 patients (44%); group 2: 25 (OH) D between 10 and < 29 ng / ml in 43 patients (51.2%) and group 3: 25 (OH) D > 30 ng / ml present in 4 patients in this population (4, 8%). Several studies have reported an association between vitamin D status and the development of type 2 diabetes. Experimental studies have suggested that vitamin D deficiency decreases insulin sensitivity, carbohydrate tolerance and β-pancreatic function. The data of this work underline the high frequency of vitamin D deficiency in the Moroccan population suffering from type 2 diabetes.

show abstract

“…Vitamin D deficiency is widespread worldwide including in countries with significant sunlight. This is a public health problem emerging [2].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%