Mechanical ventilation is nowadays a well-developed, safe, and necessary strategy for
acute respiratory distress syndrome patients to survive. However, the propagation of
microbubbles in airway bifurcations during mechanical ventilation makes the existing lung
injury more severe. In this paper, finite element and direct interface tracking techniques
were utilized to simulate steady microbubble propagation in a two-dimensional asymmetric
bifurcating airway filled with a viscous fluid. Inertial effects were neglected, and the
numerical solution of Stokes’s equations was used to investigate how gravity and surface
tension defined by a Bond (Bo) number and capillary (Ca) number influence the magnitudes
of pressure gradients, shear stresses, and shear stress gradients on the bifurcating
daughter airway wall. It is found that increasing Bo significantly influenced both the
bubble shape and hydrodynamic stresses, where Bo ≥ 0.25 results in a significant increase
in bubble elevation and pressure gradient in the upper daughter wall. Although for both Bo
and Ca, the magnitude of the pressure gradient is always much larger in the upper daughter
airway wall, Ca has a great role in amplifying the magnitude of the pressure gradient. In
conclusion, both gravity and surface tension play a key role in the steady microbubble
propagation and hydrodynamic stresses in the bifurcating airways.