This paper presents an investigation into the nonlinear dynamic behaviors of the mechanical isolation system coupled with air-bag and floating-raft subject to basement excitation in lateral directions. First, the coupling effects between the excitation source and isolation system are considered. Also, the mechanical isolation model under basic excitation and its motion equation are deduced, and then the dynamic responses are mainly investigated by using the techniques of displacement response, frequency spectrum, rotor orbit, Poincaré maps, and the bifurcation diagram. Last, the bifurcations of the mechanical isolation system with different parameters are analyzed through numerical methods, especially the effect of excitation frequency and amplitude. The result predicts that period-5 is mainly performed, with the increase of rotor speed, and the system moves into quasi-bifurcation. However, the system stays in chaos state at high rotor speed, and the vibration amplitude rises rapidly until against bearing bush. Furthermore, the effects of basement excitation on the mechanical isolation system are mainly concentrated on the stage of lower rotor speed, but with the increasing speed, the effects become weak and at the same time the vibration amplitude reduces significantly. The points projected on the Poincaré section are five, three, or two solitary attractors, in which the system stays in periodic motion. Above all, the dynamic characteristics can provide the theoretic supporting for the dynamic, vibration control and its parametric optimization of the marine mechanical isolation system coupled with air-bag and floating-raft.