Steatocystoma multiplex

Abstract

A 40-year-old man presented with multiple papules on his head and neck. The lesions had been present for about 15 years. The patient was treated for acne for 6 months, but no improvement was noted. A biopsy was performed and microscopic findings were consistent with steatocystoma multiplex.

Steatocystoma multiplex suppurativa: case report of a rare condition

“…The familial form may be related to mutation in the keratin 17, a keratin type 1 found in the sebaceous glands and hair follicles. 4 The same mutation is found in pachyonychia congenita type 2 (PC-2), with which SM may be associated, a dominant autosomal disorder that presents with nail dystrophy, palmoplantar keratoderma, oral leukoplakia, follicular keratosis and epidermal inclusion cysts. 2 , 4 , 5 , 8 In addition, SM can manifest with hypertrophic lichen planus, acrokeratosis verruciformis, natal teeth and other findings.…”

“…The clinic features of SM can resemble a number of diseases: vellus cysts, myxoid cyst, milia, acne conglobata, hidradenitis, and pseudofolliculitis, delaying the diagnosis and the proper monitoring. 1 , 2 , 4 SM suppurativa must be distinguished from severe nodulocystic acne, acne conglobata, infected fibroadenoma, and pyoderma. 6…”

“…Although it is a benign condition and most of the lesions are asymptomatic, there is an inflammatory variant called SM suppurativa. 4 , 6 In this case, there is spontaneous rupture of the cysts, suppuration and malodorous drainage, especially if secondarily colonized by bacteria. 2 , 6 , 9 Abscesses can also occur.…”

“… 1 - 3 , 7 Lesions vary from normochromic to yellow, are movable, with slow growth and liquid content most of the times. 2 , 4 …”

A Large Extragnathic Keratocystic Odontogenic Tumour

“…The cyst exhibits folds of stratified squamous epithelium, basal layer palisading, and absence of granular layer with a characteristic dense eosinophilic hyaline layer/cuticle present on the epithelium. Lobules of sebaceous glands are evident in its connective tissue wall [ 20 , 21 ]. It can be distinguished from KCOT by the presence of the flattened sebaceous structures.…”