Stem Cell Biobanks

Bardelli, Silvana

doi:10.1007/s12265-009-9143-4

Cited by 9 publications

(3 citation statements)

References 39 publications

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“…The private banking industry also benefits from the public belief in the potential future uses of privately stored HLA compatible stem cells when regenerative medicine can make use of UCB derived stem cells. Treatments for orthopaedic, cardiological and neurological applications might arise (Bardelli, 2010). In their advertising, private UCB banks define their service offer as an investment or a 'biological insurance'.…”

Section: The Organization Of Ucb Biobanksmentioning

confidence: 99%

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

Hauskeller

Beltrame

2016

BioSocieties

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Umbilical cord blood (UCB) is an important source for stem cells used in clinical treatments. For this purpose, UCB has to be collected at birth and stored in biobanks. The discourse about UCB biobanking practices commonly holds that it occurs in two opposite economies, the public sector and a competing private one. They correspond with moral economies of gift-giving in a redistributive economy versus private ownership of cord blood in a market economy. Our analysis of UCB banking in Europe shows that this opposition narrative is both empirically and analytically unsatisfactory. Using the analytic concepts of entanglement (Callon) and biomedical platforms (Keating and Cambrosio), we demonstrate how the network of actors, objects, interests and practices in biobanking creates different kinds of value and shared issues across public and private services. Our case study illustrates how the interrelation between technical, ethical, economic and logistical considerations plays out and generates a field of practices where redistributive and market economies coexist, are co-dependent and hybridize each other. The narrative of opposition therefore can inform STS studies regarding the normative values written into the public facing side of biobanking, but bioeconomic analyses benefit from building on concepts that enable the examination of the complex interrelations between the wider network of heterogeneous elements on which UCB banking relies.

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Section: The Organization Of Ucb Biobanksmentioning

confidence: 99%

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

Hauskeller

Beltrame

2016

BioSocieties

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“…In the case of ASCs and/or iPSCs, one proposed idea is to create a biobank of tissues for active military personnel, whereby prior to deployment soldiers will provide tissue biopsies for long-term storage and eventual self-treatment in the event of injury. Biobanks are commonly utilized for infant cord blood [104], and act as tissue and/or cell repositories, holding an immediate and safe reservoir of cells that can be therapeutically applied.…”

Section: Auxiliary Applicationsmentioning

confidence: 99%

Stem cell applications in military medicine

Christopherson

Nesti

2011

Stem Cell Res Ther

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There are many similarities between health issues affecting military and civilian patient populations, with the exception of the relatively small but vital segment of active soldiers who experience high-energy blast injuries during combat. A rising incidence of major injuries from explosive devices in recent campaigns has further complicated treatment and recovery, highlighting the need for tissue regenerative options and intensifying interest in the possible role of stem cells for military medicine. In this review we outline the array of tissue-specific injuries typically seen in modern combat - as well as address a few complications unique to soldiers - and discuss the state of current stem cell research in addressing each area. Embryonic, induced-pluripotent and adult stem cell sources are defined, along with advantages and disadvantages unique to each cell type. More detailed stem cell sources are described in the context of each tissue of interest, including neural, cardiopulmonary, musculoskeletal and sensory tissues, with brief discussion of their potential role in regenerative medicine moving forward. Additional commentary is given to military stem cell applications aside from regenerative medicine, such as blood pharming, immunomodulation and drug screening, with an overview of stem cell banking and the unique opportunity provided by the military and civilian overlap of stem cell research.

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“…Moreover, hCBMSCs have advantages partly related to the immaturity of newborn cells compared with adult stem cells, including possible escape from immune rejection. For these reasons, human umbilical CB have been increasingly banked and used as a source of marrow repopulating stem cells in patients with BM deficit or inborn errors of metabolism [14]. To summarize, both adult and neonatal tissues are being explored as valid sources for clinically applicable protocols.…”

Section: Stem Cell Sourcesmentioning

confidence: 99%

Stem Cell Update: Highlights from the 2010 Lugano Stem Cell Meeting

Bardelli

Astori

Sürder

et al. 2010

J. of Cardiovasc. Trans. Res.

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The 2010 edition of the Lugano Stem Cell Meeting, under the auspices of the Swiss center of excellence in cardiovascular diseases "Cardiocentro Ticino" and the Swiss Stem Cell Foundation, offered an update on clinical, translational, and biotechnological advances in regenerative science and medicine pertinent to cardiovascular applications. Highlights from the international forum ranged from innate mechanisms of heart repair, safety, and efficacy of ongoing and completed clinical trials, novel generations of stem cell biologics, bioengineered platforms, and regulatory processes. In the emerging era of regenerative medicine, accelerating the critical path from discovery to product development will require integrated multidisciplinary teams to ensure timely translation of new knowledge into validated algorithms for practice adoption.

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Stem Cell Biobanks

Cited by 9 publications

References 39 publications

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

Stem cell applications in military medicine

Stem Cell Update: Highlights from the 2010 Lugano Stem Cell Meeting

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