Stem/Progenitor Cells in Vascular Regeneration

Zhang, Li; Xu, Qingbo

doi:10.1161/atvbaha.114.303809

Cited by 58 publications

(39 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…105 Vascular tissue-resident or adult stem cells have been discovered and display variable capacities for differentiation. [106][107][108] Stem/ progenitor cells can differentiate into vascular cell lineages, which may contribute to the regenerative process and could be useful for the treatment of atherosclerosis.…”

Section: Stem/progenitor Cellsmentioning

confidence: 99%

Reactive Oxygen Species Generation and Atherosclerosis

Nowak

Deng

Ruan

et al. 2017

ATVB

Self Cite

136

View full text Add to dashboard Cite

Section: Stem/progenitor Cellsmentioning

confidence: 99%

Reactive Oxygen Species Generation and Atherosclerosis

Nowak

Deng

Ruan

et al. 2017

ATVB

Self Cite

136

View full text Add to dashboard Cite

“…[15][16][17] In addition, it has been shown to be involved in promoting endothelial migration 18 and enhancing endothelial barrier function, which is necessary for vessel maturation. 19 Taken together CXCL12 may enhance angiogenesis during wound healing by recruiting progenitor cells along with direct interaction with endothelial cells.…”

Section: Chemokines Regulating Angiogenesismentioning

confidence: 99%

Chemokine Regulation of Angiogenesis During Wound Healing

Bodnar

2015

Advances in Wound Care

152

104

View full text Add to dashboard Cite

“…However, recent studies have shown that various progenitor and non-progenitor cell subsets could be a source of VSMCs. Those include SMC progenitors (Kumar et al 2010), pericytes (Orekhov et al 2014), vascular resident and non-resident MSCs (Zhang and Xu 2014), adipose stromal cells (Merfeld-Clauss et al 2014), and mature ECs that could undergo endothelialmesenchymal transition (Lin et al 2012). However, the portion of non-local cells that are involved in the neointima formation is still unclear.…”

Section: Smooth Muscle Cell Progenitor Cellsmentioning

confidence: 99%

Vascular stem/progenitor cells: current status of the problem

2015

View full text Add to dashboard Cite

Stem/progenitor cells residing in the vascular wall of post-natal vessels play a crucial role in angiogenesis and vascular regeneration after damage. There are four major populations of vascular-resident stem/progenitor cells with differentiated clonogenic and proliferative potential, namely mesenchymal stem cells, pericytes, endothelial progenitor cells, and smooth muscle progenitor cells. These progenitors reside in vascular stem cell niches, which are more likely to be in the adventitia, a vascular wall layer in which increased concentration of stem cell surface markers has been shown. Indeed, vascular resident progenitors are not uniformly distributed across the vessel wall and the circulatory system. The heterogeneity of such a distribution could contribute to the differentiated susceptibility of various vessel regions to chronic vascular diseases such as atherosclerosis. In cardiovascular pathology, adult vascular resident progenitors could play either a negative or a positive role.

show abstract

Stem/Progenitor Cells in Vascular Regeneration

Cited by 58 publications

References 72 publications

Reactive Oxygen Species Generation and Atherosclerosis

Reactive Oxygen Species Generation and Atherosclerosis

Chemokine Regulation of Angiogenesis During Wound Healing

Vascular stem/progenitor cells: current status of the problem

Contact Info

Product

Resources

About