Step‐wise treatment of athlete’s foot (tinea pedis) using isoconazole combined with a corticosteroid followed by isoconazole alone

Olkhovskaya, K. B.; Perlamutrov, Yu. N.

doi:10.1111/j.1439-0507.2008.01613.x

Cited by 6 publications

(3 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pruritus, burning and pain associated with tinea pedis with bacterial superinfection had a significant negative effect on this patient's quality of life (QoL). As seen in previous case reports, a 2‐week treatment regimen with Travocort cream (containing the imidazole ISN 0.1% and the corticosteroid diflucortolone valerate) was effective in improving the clinical signs of tinea pedis and in alleviating the symptoms that most impacted the patient's QoL. Furthermore, the regimen was safe for use in patients with diabetes consistent with previous reports .…”

Section: Discussionsupporting

confidence: 87%

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Friedrich¹

2013

Mycoses

View full text Add to dashboard Cite

Undetected tinea pedis in a patient with diabetes can lead to serious bacterial infections with potentially serious consequences, such as foot amputations. Here we report on a 60-year-old patient with diabetes presenting with pain, severe pruritus, and malodour in the foot's interdigital area, and subsequently, diagnosed with inflammatory tinea pedis with bacterial superinfection. The patient was successfully treated with Travocort cream containing isoconazole nitrate 1% and diflucortolone valerate 0.1%; marked improvement occurred within 5 days.

show abstract

Section: Discussionsupporting

confidence: 87%

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Friedrich¹

2013

Mycoses

View full text Add to dashboard Cite

show abstract

“…Although the clinical results of all these studies were considered as satisfactory, it was observed that, by means of the Warburg assay, antifungal activity of clotrimazole, econazole and ketoconazole was significantly impaired when triamcinolone acetonide or prednisolone‐21‐hemisuccinate‐sodium at high concentrations (10–25 times higher than the concentrations of imidazoles) were present in the test flasks 13 . Since 2008, the most studied combination was isoconazole/diflucortolone 14–35 . In particular, two sponsor‐free studies were carried out at the Dermatology Unit of the University of Milan in patients with tinea cruris 27 and tinea corporis 35 .…”

mentioning

confidence: 99%

“…This study in atopic children with tinea corporis superinfected by S. aureus confirmed that the association isoconazole/diflucortolone was useful and safe. Anecdotic cases of patients successfully treated with this combination were reported in tinea faciei , 31,33 tinea corporis , 19–21,31–33 tinea cruris , 16–18,33 tinea pedis , 25,26,30 intertrigo 22–24,34 and balanitis by Candida albicans 24 …”

mentioning

confidence: 99%

The association topical antifungals/topical corticosteroids in superficial mycoses of the skin: A critical review of the literature and personal experience

Veraldi

Bortoluzzi

2022

Dermatologic Therapy

View full text Add to dashboard Cite

Clotrimazol und Ciclopiroxolamin jeweils in Kombination mit Methylprednisolonaceponat in magistralen Rezepturen

et al. 2017

View full text Add to dashboard Cite

The combination of topical fungicide and glucocorticoids has been proven as a successful therapy of cutaneous mycoses with accompanying inflammatory reactions, particularly when used at an early stage. Various national and international therapeutic guidelines recommend this practice. In this context, two individually manufactured formulations have been developed and tested for stability: the combination of methylprednisolone aceponate-a topical glucocorticoid with the therapeutic index of 2.0-with clotrimazole and with ciclopirox olamine, respectively. This has been conducted in compliance with the requirements for quality controlled extemporaneous formulations and the legal framework of the German Pharmacy Working Regulations (Apothekenbetriebsordnung). There are now two formulations for clinical use that are microbiologically, physically, and chemically stable, which combine methylprednisolone aceponate-a glucocorticoid with a good risk-benefit ratio-with the broad-spectrum fungicides clotrimazole and, for the first time, ciclopirox olamine.

show abstract

Step‐wise treatment of athlete’s foot (tinea pedis) using isoconazole combined with a corticosteroid followed by isoconazole alone

Cited by 6 publications

References 1 publication

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

The association topical antifungals/topical corticosteroids in superficial mycoses of the skin: A critical review of the literature and personal experience

Clotrimazol und Ciclopiroxolamin jeweils in Kombination mit Methylprednisolonaceponat in magistralen Rezepturen

Contact Info

Product

Resources

About