Stereochemical investigations of bioactive dihydrobenzofuran-type lignanamides from Solanum lyratum: chiral resolution, in vitro and in silico profiling

Abstract

Six pairs of enantiomeric dihydrobenzofuran-type lignanamides consisting of nine undescribed compounds (1a, 2a/2b−3a, 4b−6a/6b), along with a previously undescribed racemic mixture (7), were isolated from Solanum lyratum (Solanaceae), and the...