Steroid Cell Tumor of the Ovary in an Adolescent: A Rare Case Report

Abstract

Steroid cell tumors (SCTs) of the ovary are a rare subgroup of sex cord tumors, account for less than 0.1% of all ovarian tumors, and also will present at any age. These tumors can produce steroids, especially testosterone, and may give symptoms like hirsutism, hair loss, amenorrhea, or oligomenorrhea. For the evaluation of androgen excess, testosterone and dehydroepiandrosterone sulfate (DHEA-S) are the first laboratory tests to be measured. A pelvic ultrasound and a magnetic resonance imaging are useful radiologic imaging techniques. Although steroid cell tumors are generally benign, there is a risk of malignant transformation and clinical malignant formation. Surgery is the most important and hallmark treatment.

Steroid cell tumour of the ovary: a case report with review of literature

“…Steroid cell tumours are grouped under sex cord stromal tumours, and they are usually unilateral, benign in nature and formed by proliferation of steroid cells. 1 Steroid cell tumours generally show androgenic symptoms like amenorrhea, abnormal hair growth in the face and body, hair loss, deepening of voice and increased libido. 1,3 Steroid cell tumours of the ovary are identified based on the absence of pathognomonic features, seen in other androgen secreting ovarian tumours such as Reinke Crystals, Call-Exner bodies, and prominent nucleoli.…”

“…1,2 Virilizing ovarian tumours account for less than 5% of all ovarian tumours. 1,2 Steroid cell tumours produce steroids especially testosterone and generally show androgenic symptoms like amenorrhea, abnormal hair growth in the face and body, hair loss, deepening of voice and increased libido.…”

“…1,2 Virilizing ovarian tumours account for less than 5% of all ovarian tumours. 1,2 Steroid cell tumours produce steroids especially testosterone and generally show androgenic symptoms like amenorrhea, abnormal hair growth in the face and body, hair loss, deepening of voice and increased libido. 1,3 According to the WHO, the androgen secreting steroid cell tumours are further classified as either pure sertoli, sertoli-Leydig, gynandroblastomas, or steroid cell, NOS, wherein steroid cell, NOS is the most common type accounting for approximately 60% of steroid cell tumours.…”

“…1,2 Steroid cell tumours produce steroids especially testosterone and generally show androgenic symptoms like amenorrhea, abnormal hair growth in the face and body, hair loss, deepening of voice and increased libido. 1,3 According to the WHO, the androgen secreting steroid cell tumours are further classified as either pure sertoli, sertoli-Leydig, gynandroblastomas, or steroid cell, NOS, wherein steroid cell, NOS is the most common type accounting for approximately 60% of steroid cell tumours. 4 Historically these tumours have been referred to as lipoid cell tumours, lipid cell tumours, luteomas, masculinovoblastomas, hypernephroid tumours, adrenallike tumours and adrenal rest tumours, since the exact lineage of the tumour is not known.…”

Ovarian Steroid Cell Tumor: Report Of Four Cases

“…Steroid cell tumors are rare sex cord stromal tumors and account for less than 0.1% of all ovarian tumors (1) .…”