Steroid-fullerene hybrids: a review

Ibrahim‐Ouali, Malika; DUMUR, Frédéric

doi:10.24820/ark.5550190.p011.734

Cited by 3 publications

(4 citation statements)

References 46 publications

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“…The first issue of reviews & accounts was published in 2007. Authors publishing in the reviews & accounts issues in recent years have included: Thomas Böttcher, 3 Raju Chowhan, 4 Jose Elguero, 5 Ahmed Elwahy, 6 Malika Ibrahim-Quali, 7,8 Alain Krief, 9,10 Paolo Quadrelli 11 and D.S. Ramakrishna.…”

Section: What Makes Arkivoc So Special?mentioning

confidence: 99%

Arkivoc, the platinum open access journal for organic chemistry, as it approaches its 25th anniversary

Aanonson¹

2023

Arkivoc

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Arkivoc is an open access journal for organic chemistry, which since its foundation by Alan Katritzky in 2000, has been free to readers and authors. The journal has a humanitarian mission and publishes many papers written by authors in developing countries. The majority of its workforce are unpaid volunteers working part-time as scientific editors and in other roles. In 2020 it achieved the DOAJ's Seal award for best practice in open access publication.Published on line 03-01-2023 © AUTHOR(S) Free to readers and authorsArkivoc is an open access journal for organic chemistry, which is free to both readers and authors. When Alan and Linde Katritzky founded the journal in 2000 with a charitable donation, their aim was that the journal should particularly help authors and readers outside the US and Western Europe.Whilst attending conferences in India as a plenary speaker in the 1990s, Alan Katritzky heard first-hand about the dire problems, which Indian organic chemists had with access to journals and getting their papers published. He was also aware that these same problems were being felt in many other countries. Over several years, academic libraries had been cancelling journals because of financial problems and publishers had been responding by raising prices and the end result was negative for everybody. Organic chemistry journals were amalgamated and sometimes they ceased publication. Consequently, readers were losing access to new research. Moreover, whilst the situation was difficult in the US and Western Europe, it was much worse in developing countries. Alan Katritzky founded Arkivoc for humanitarian reasons. His aim was that the journal would enable organic chemists in developing countries to more easily publish their results and that all readers would have access to their papers.Open access journals adhere to the principle that publicly funded research should be available to everybody, and that scientific research results should be widely accessible. Arkivoc is categorized as a platinum open access journal, because it is free to both readers and authors. This distinguishes it from gold open access journals, which are free to readers but oblige authors to pay an article processing charge. The first gold open access journal for organic chemistry was Molecules, which was first published in 1996. When Arkivoc started publication in 2000, it was the first platinum open access journal for organic chemistry.Brainard 2 has identified a gradually increasing trend towards open access publication over the last three decades. Indeed, he estimated that 45% of chemical literature was open access in 2019, including both green open access documents in repositories and papers in hybrid journals. With hindsight, one can see that Alan Katritzky was a visionary when he started Arkivoc as a platinum open access journal in 2000. Peer reviewPapers published in Arkivoc go through a rigorous, two stage, peer review system. Newly received manuscripts are considered by a Primary Review Committee and those that pass this step are th...

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Section: What Makes Arkivoc So Special?mentioning

confidence: 99%

Arkivoc, the platinum open access journal for organic chemistry, as it approaches its 25th anniversary

Aanonson¹

2023

Arkivoc

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“…[29] A review containing the work developed in this field by our research groups has recently been published. [30] On the other hand, incorporating carbohydrates into hybrid systems is being used for their ability to interact with lectins on the cell surface, and for their participation in biological processes such as cell growth and differentiation. [31] Due to these characteristics, they have been covalently linked to [60]fullerene, and the conjugates obtained tested as agents against bacterial and viral infections.…”

Section: Introductionmentioning

confidence: 99%

“…The morphology and particle size in aqueous solution were determined by transmission electron microscopy [29] . A review containing the work developed in this field by our research groups has recently been published [30] …”

Section: Introductionmentioning

confidence: 99%

Synthesis of [60]Fullerene Hybrids Endowed with Steroids and Monosaccharides: Theoretical Underpinning as Promising anti‐SARS‐CoV‐2 Agents

et al. 2023

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Cyclopropanation reactions between C60 and different malonates decorated with monosaccharides and steroids using the Bingel‐Hirsch methodology have allowed the obtention of a new family of hybrid compounds in good yields. A complete set of instrumental techniques has allowed us to fully characterize the hybrid derivatives and to determine the chemical structure of monocycloadducts. Besides, the proposed structures were investigated by cyclic voltammetry, which evidenced the exclusive reductive pattern of fullerene Bingel‐type monoadducts. Theoretical calculations at the DFT‐D3(BJ)/PBE 6‐311G(d,p) level of the synthesized conjugates predict the most stable conformation and determine the factors that control the hybrid molecules′ geometry. Some parameters such as polarity, lipophilicity, polar surface area, hydrophilicity index, and solvent‐accessible surface area were also estimated, predicting its potential permeability and capability as cell membrane penetrators. Additionally, a molecular docking simulation has been carried out using the main protease of SARS‐CoV‐2 (Mpro) as the receptor, thus paving the way to study the potential application of these hybrids in biomedicine.

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“…Research into steroid total synthesis continues to this day. [35][36][37][38] The introduction of heteroatom or replacement of one or more carbon atoms in a steroidal molecule by a heteroatom affects the chemical properties of that particular steroid and often results in alterations of its biological activities, which sometimes may be useful. Azasteroids especially express numerous biological activities.…”

Section: Introductionmentioning

confidence: 99%

Steroidal lactams: a review

Ibrahim‐Ouali¹,

DUMUR²

2022

Arkivoc

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Steroidal lactams are also a class of steroid derivatives that were synthesized and modified to increase the biological activity of steroids. Their synthesis is a stimulating challenge to the scientist, often claiming the development of new and generally useful reactions. Some of them have been tested successfully as anticancer drugs against different types of leukemia. Recent developments in the syntheses of steroidal lactams are described herein. The biological activities of those steroidal derivatives for which data are available are given.

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Steroid-fullerene hybrids: a review

Cited by 3 publications

References 46 publications

Arkivoc, the platinum open access journal for organic chemistry, as it approaches its 25th anniversary

Arkivoc, the platinum open access journal for organic chemistry, as it approaches its 25th anniversary

Synthesis of [60]Fullerene Hybrids Endowed with Steroids and Monosaccharides: Theoretical Underpinning as Promising anti‐SARS‐CoV‐2 Agents

Steroidal lactams: a review

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