Steroid-induced hypocalcaemia with tetany in a patient with hypoparathyroidism

Oikonomou, Dimitrios; Laina, Ageliki; Xydaki, Aikaterini; Christopoulos, Constantinos

doi:10.1136/bcr-2014-207562

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Some clinical situations may destabilize a welladjusted treatment or even hinder a proper control of calcium levels, including gastrointestinal infections, urgent hospitalizations, medications affecting the absorption of nutrients or other medications (orlistat, cholestyramine, and glucocorticoids, among others), as well as conditions associated with spontaneous malabsorption (inflammatory bowel disease, celiac disease, or malabsorption due to other causes) or iatrogenic (such as post-bariatric surgeries) and difficulties in the ingestion of medications by mouth, as seen in wide surgical resections due to laryngeal cancer (2,(118)(119)(120)(121)(122)(123). The metabolic control during pregnancy and lactation in patients with hypoparathyroidism will be discussed in Section 10.…”

Section: Treatment Of Chronic Hypocalcemiamentioning

confidence: 99%

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism

Maeda¹,

Moreira²,

Borba³

et al. 2018

Archives of Endocrinology and Metabolism

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Objective To present an update on the diagnosis and treatment of hypoparathyroidism based on the most recent scientific evidence. Materials and methods The Department of Bone and Mineral Metabolism of the Sociedade Brasileira de Endocrinologia e Metabologia (SBEM; Brazilian Society of Endocrinology and Metabolism) was invited to prepare a document following the rules set by the Guidelines Program of the Associação Médica Brasileira (AMB; Brazilian Medical Association). Relevant papers were retrieved from the databases MEDLINE/PubMed, LILACS, and SciELO, and the evidence derived from each article was classified into recommendation levels according to scientific strength and study type. Conclusion An update on the recent scientific literature addressing hypoparathyroidism is presented to serve as a basis for the diagnosis and treatment of this condition in Brazil.

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Section: Treatment Of Chronic Hypocalcemiamentioning

confidence: 99%

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism

Maeda¹,

Moreira²,

Borba³

et al. 2018

Archives of Endocrinology and Metabolism

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“…[10] However, serious hypocalcaemic symptoms should be relieved by intravenous calcium supplementation as quickly as possible. [11–16] Moreover, intravenous calcium administration to patients with refractory hypocalcaemia is a major reason for prolonged hospitalization after thyroid surgery. [17]…”

Section: Introductionmentioning

confidence: 99%

Role of oral calcium supplementation alone or with vitamin D in preventing post-thyroidectomy hypocalcaemia

Xing¹,

Wang

et al. 2019

Medicine

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“…Perioperative glucocorticoid (GC) treatment may also exacerbate underlying hypocalcemia and hypoparathyroidism in the postoperative period for patients with 22q11DS. Previous research has suggested that in patients with parathyroid dysfunction, GC treatment may induce clinically significant hypocalcemia [ 9 , 10 ]. GC administration may reduce dietary calcium absorption and may also increase renal calcium excretion.…”

Section: Discussionmentioning

confidence: 99%

Postoperative Hypocalcemia following Non-Cardiac Surgical Procedures in Children with 22q11.2 Deletion Syndrome

Arganbright

Tracy

Feldt

et al. 2022

Genes

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The guidelines for management of children with 22q11.2 deletion syndrome (22q11DS) highlight the risk for developing hypocalcemia after surgery and recommend monitoring calcium perioperatively. Despite this guidance, little has been published on postoperative hypocalcemia and 22q11DS. Our goals were to evaluate the frequency of perioperative calcium monitoring and examine how often postoperative hypocalcemia was identified. This is a retrospective chart review of patients in our 22q Center’s repository. Inclusion criteria were a diagnosis of 22q11DS and a history of a non-cardiac surgical procedure. Data collected included all non-cardiac surgeries and perioperative calcium labs. In total, 68 patients were included and underwent 305 on-cardiac surgeries. Patients in only 17% of these surgeries had postoperative calcium testing, but of those tested, 58% showed hypocalcemia. Patients with history of hypocalcemia at the time of chart review undergoing non-cardiac surgeries were tested postoperatively 40% of the time; however, 67% of these had hypocalcemia. Similarly, for patients without history of hypocalcemia, postoperative testing occurred 60% of the time, with 52% of these having hypocalcemia. This study demonstrates that postoperative hypocalcemia in children with 22q11DS following non-cardiac surgeries is common and affects patients both with and without prior history of hypocalcemia. These data support establishing a protocol for perioperative testing/management of hypocalcemia for patients with 22q11DS.

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Steroid-induced hypocalcaemia with tetany in a patient with hypoparathyroidism

Cited by 7 publications

References 11 publications

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism

Role of oral calcium supplementation alone or with vitamin D in preventing post-thyroidectomy hypocalcaemia

Postoperative Hypocalcemia following Non-Cardiac Surgical Procedures in Children with 22q11.2 Deletion Syndrome

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