Sterol regulatory element binding transcription factor 1 expression and genetic polymorphism significantly affect intramuscular fat deposition in the longissimus muscle of Erhualian and Sutai pigs1

Low protein diet up-regulate intramuscular lipogenic gene expression and down-regulate lipolytic gene expression in growth–finishing pigs

“…The entire pathway of palmitate synthesis from malonyl-CoA in mammals is catalyzed by FAS (Smith et al, 2003). Some studies indicated that a positive relation between IMF content and expression of SREBP-1 mRNA in muscle tissue of pigs exists (Chen et al, 2008). Additionally, there is evidence that SCD participates in triglyceride syntheses by providing a better accessible pool of monounsaturated fatty acids (Man et al, 2006).…”

Chromosomal localization of nine porcine genes encoding transcription factors involved in adipogenesis

“…Association studies between polymorphisms in the PPARG gene and meat quality traits were performed in different pig populations (Grindflek et al, 2004;Kim et al, 2004), but no convincing associations were found. Recently, two single nucleotide polymorphisms (SNP) in the SREBF1 gene have been identified and it has been suggested that these SNPs may be considered as genetic markers for improving intramuscular fat content in pigs (Chen et al, 2008).…”

Research Article Study of genetic variability in pigs after the traditional breeding program.

“…A study performed by Óvilo et al (2006) in commercial hybrid pigs (Landrace x Taihu x Large-White) found two polymorphisms of the MC4R gene and the AA, AG, and GG genotypes with the following frequencies 8, 36, and 56%, respectively, and observed that none of the alleles would have a clear advantage in selection processes. Chen et al (2008) carried out experiments to clarify the role of SREBF1 in the deposition of intramuscular fat (IMF) in crossbred Erhualian x Duroc animals, called Sutai. They found three AA genotypes with a frequency of 50%, AB (36%), and BB (14%).…”