Stimuli‐Responsive Controlled Drug Release from a Hollow Mesoporous Silica Sphere/Polyelectrolyte Multilayer Core–Shell Structure

Abstract

Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the release of ibuprofen (IBU) from spheres with and without coatings of sodium polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH).

Spatial Confinement of a Co3O4 Catalyst in Hollow Metal–Organic Frameworks as a Nanoreactor for Improved Degradation of Organic Pollutants

“…19 However, despite their success in some areas, this technology still suffers from tedious post-treatment processes of the template-engaged synthetic approach and limited functionality of the amorphous silica, 20 which make it far from a routine task in fabricating our nanoreactor. Luckily, metal−organic frameworks (MOFs), emerging as a new class of hybrid functional materials with large surface area, favorable thermal stability, and tailorable chemistry, 21−23 open new opportunity for the conceivement.…”

Surface-Functionalized Periodic Mesoporous Organosilica Hollow Spheres

“…The well-organized pores and hollow morphology can make it suitable for applications in confined nanocatalysts, biosensors, targeted drug and gene delivery, enzyme encapsulation, and nanoreactors. [1][2][3][4][5][6] There have been reports about synthesis of silica hollow spheres by several methods such as sonochemical, 7 solid particle templates, [8][9][10] surfactant/vesicle templates, [11][12][13][14][15][16][17] and emulsion templating technology. 18,19 However, only several reports have occasionally involved the synthesis of hollow spheres with ordered porous wall structures.…”

Preparation and properties of antibacterial TiO2@C/Ag core–shell composite

“…Nanomaterials with core-shell structure have been extensively studied because of their multifunctional properties and various applications, such as drug delivery [8] and increasing their solubility and stability [9,10] and altering the emission properties of quantum dots [11,12]. In addition to the above-mentioned characteristics, core-shell nano-oxides such as TiO 2 @X and ZnO@X also have unique antibacterial properties that have attracted attention to this area in recent years [13][14][15][16].…”