Detailed results from a multi-zone phenomenological simulation of partially premixed advanced-injection low-pilot-ignited natural-gas low-temperature combustion are presented with a focus on early injection timings (the beginning of (pilot) injection (BOI)) and very small diesel quantities (2-3 per cent of total fuel energy). Combining several aspects of diesel and spark ignition engine combustion models, the closed-cycle simulation accounted for diesel autoignition, diesel spray combustion, and natural-gas combustion by premixed turbulent flame propagation. The cylinder contents were divided into an unburned zone, several pilot fuel zones (or 'packets') that modelled diesel evaporation and ignition, a flame zone for natural-gas combustion, and a burned zone. The simulation predicted the onset of ignition, cylinder pressures, and heat release rate profiles satisfactorily over a wide range of BOIs (20-60u before top dead centre (before TDC)) but especially well at early BOIs. Strong coupling was observed between pilot spray combustion in the packets and premixed turbulent combustion in the flame zone and, therefore, the number of ignition centres (packets) profoundly affected flame combustion. The highest local peak temperatures (greater than 2000 K) were observed in the packets, while the flame zone was much cooler (about 1650 K), indicating that pilot diesel spray combustion is probably the dominant source of engine-out emissions of nitrogen oxide (NO x ). Further, the 60u before TDC BOI yielded the lowest average peak packet temperatures (about 1720 K) compared with the 20u before TDC BOI (about 2480 K) and 40u before TDC BOI (about 2700 K). These trends support experimental NO x trends, which showed the lowest NO x emissions for the 60u, 20u, and 40u before TDC BOIs in that order. Parametric studies showed that increasing the intake charge temperature, pilot quantity, and natural-gas equivalence ratio all led to higher peak heat release rates and hotter packets but the pilot quantity and intake temperature affected the potential for NO x formation to a greater extent.