Urban sprawl and the shortage of proper sanitary infrastructures significantly jeopardize public health and urban sustainability. The problem is further aggravated as a result of the rapid urbanization and urban sprawl. This study investigated the relationship between urban sprawl and sanitation risk conditions in a rapidly growing city in India. This was accomplished by investigating changes in urban sprawl areas between the periods 2000–2020 using multispectral satellite images and Shanon's entropy model and studying the pattern of spatial variations in basic sanitation services derived from the 100 household‐based surveyed WASH (water availability, sanitation, and hygiene) data collected in 2018 before COVID‐19 from 45 sprawl regions. Spatial statistical techniques, namely, the inverse distance weighted (IDW) interpolation and the multicriteria decision technique, were employed for neighborhood analysis and assessing sanitation risks inside the sprawl region. Results showed that Raipur exhibited urban sprawl and around 93.68% of the sprawl area was classified between high (6.47%)‐ and medium (80.52%)‐risk zones.