Streptococcus agalactie como agente etiológico de Doença Sexualmente Transmissível

Abstract

Abstract:Streptococcus agalactiae is an important microorganism involved in a number of conditions in pregnant women, newborns, elderly people (over 65 years of age) and individuals with chronic disabling illnesses. This pathogen is infrequently found among patients outside this age range or clinical profile(1-5) and is rarely reported in the etiology of sexually transmitted diseases. Here we describe a case of an otherwise healthy 19 year-old male, who presented with ulcerative genital and oral lesions in association with urethral and ocular discharge, suggestive of Streptococcus agalactiae infection acquired through sexual contact. Keywords: Oral ulcer; Sexually transmitted diseases; Skin ulcer; Streptococcus agalactiae; Urethritis Resumo: O Streptococcus agalactie é um importante micro-organismo causador de doenças em gestantes, neonatos, idosos (maiores de 65 anos de idade), e portadores de doenças crônicas debilitantes, sendo um patógeno incomum em pacientes que não se enquadrem nestas faixas etárias ou perfil clíni-co (1-5), e, raramente, é descrito como agente causador de doenças sexualmente transmissíveis. Descrevemos o caso de um adulto jovem hígido de 19 anos, apresentando lesões ulceradas genitais e oral, assim como corrimento uretral e ocular, sugestivas de terem sido causadas pelo Streptococcus agalactie, e adquiridas através do contato sexual (doenças sexualmente transmissíveis).

Physiological impact of transposable elements encoding DDE transposases in the environmental adaptation of Streptococcus agalactiae

“…It was also reported to be a food contaminant. Such ability to survive and develop in numerous different environments indicates a large capability of adaptation (Edwards et al , 2011; Evans et al , 2008; Farley, 2001; Frey et al , 2011; Richards et al , 2011; van der Mee-Marquet et al , 2008, 2009).…”

Streptococcus agalactiae and genital ulcers in a heterosexual male

“…There is no specific antibiotic for genital S. agalactiae infection. Penicillin, ampicillin, cephalosporin, carbapenics, macrolides, and quinolones have been used with good results [5][6][7]. Our conclusion: In a promiscuous, heterosexual adult with genital ulcers, S. agalactiae was found.…”

“…The latter can lead to heart valve lesions, endocarditis, pneumonia, osteomyelitis, and meningitis [1,2]. S. agalactiae has been found in ulcers in the oral cavity or on the genitals [5,6]. It has also been found in urethral discharge and is estimated to be present in 1.5% of nongonococcal urethritis cases [6].…”

“…In this regard, Lucks [10] raised the possibility of acquiring S. agalactiae, through a traumatic abrasion during sexual intercourse, with subsequent balanitis. On the other hand, Frey et al [5] reported S. agalactiae in painful ulcers on the penis and in the oral cavity of an adolescent, five days after vaginal intercourse and oral sex, with an unknown partner and without the use of a condom. Because S. agalactiae is isolated from the rectum, perineum, vaginal discharge, cervix, and urethra from sexually active people with multiple partners, transmission through sexual contact has been suggested [1].…”

“…Most people colonized with S. agalactiae will not experience invasive disease, but entry of the germ into niches outside the gastrointestinal tract or vaginal mucosa can result in infectious events. Although they were not evaluated in the case presented, the virulence of the germ, the immune fragility of the individual, diabetes, liver disease, cancer, neurological disorders and heart or kidney failure, can create conditions that facilitate the transition of S. agalactiae from asymptomatic colonizer to invasive pathogen [1,2,3,5].…”