Streptomyces sp. 173, an insecticidal micro-organism from marine

Xiong, Li-Xia; Li, J.; Kong, Fan‐Zhou

doi:10.1046/j.1472-765x.2003.01437.x

Cited by 36 publications

(16 citation statements)

References 13 publications

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“…The brine shrimp larva lethality test is commonly used as a cytotoxicity model in antitumor and pesticidal assays (Hu et al, 2000;Carballo et al, 2002;Xiong et al, 2004). The test was performed as previously described (Zhang et al, 2012).…”

Section: Cytotoxicity Against Brine Shrimp Larvamentioning

confidence: 99%

Isolation and characterization of bioactive fungi from shark Carcharodon carcharias’ gill with biopharmaceutical prospects

Zhang

Han

Feng

et al. 2015

Chin. J. Ocean. Limnol.

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Until recently, little was known about the fungi found in shark gills and their biomedicinal potential. In this article, we described the isolation, bioactivity, diversity, and secondary metabolites of bioactive fungi from the gill of a shark ( Carcharodon carcharias ). A total of 115 isolates were obtained and grown in 12 culture media. Fifty-eight of these isolates demonstrated signifi cant activity in four antimicrobial, pesticidal, and cytotoxic bioassay models. Four randomly selected bioactive isolates inhibited human cancer cell proliferation during re-screening. These active isolates were segregated into 6 genera using the internal transcribed spacer-large subunit (ITS-LSU) rDNA-sequence BLAST comparison. Four genera, Penicillium , Aspergillus , Mucor , and Chaetomium were the dominant taxa. A phylogenic tree illustrated their intergenera and intragenera genetic diversity. HPLC-DAD-HRMS analysis and subsequent database searching revealed that nine representative strains produced diverse bioactive compound profi les. These results detail the broad range of bioactive fungi found in a shark's gills, revealing their biopharmaceutical potential. To the best of our knowledge, this is the fi rst study characterizing shark gill fungi and their bioactivity.

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Section: Cytotoxicity Against Brine Shrimp Larvamentioning

confidence: 99%

Isolation and characterization of bioactive fungi from shark Carcharodon carcharias’ gill with biopharmaceutical prospects

Zhang

Han

Feng

et al. 2015

Chin. J. Ocean. Limnol.

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“…For this purpose, they have the ability to produce a wide range of secondary metabolites, such as antibacterial and antifungal substances. 68 Nutrients in nature are usually present in a wide range of complexities; therefore, microorganisms must have the necessary tools to succeed in their utilization. For this purpose, 819 potentially secreted proteins have been predicted to operate in S. coelicolor.…”

Section: Streptomycesmentioning

confidence: 99%

Carbon source regulation of antibiotic production

et al. 2010

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“…Therefore, numerous studies have focused on the isolation of bacterial metabolites using different organic solvents and evaluation of their biological actions. Xiong et al (2004) isolated 331 strains from seawater and sea sediments from Beidiahe and Dagang on the east coast of China and screened them for their insecticidal qualities. The screening was carried out using bioassay of brine shrimp and the insect pest Helicoverpa armigera.…”

Section: Resultsmentioning

confidence: 99%

High Performance Thin Layer Chromatography (HPTLC) profile of an insecticidal compound of Trochus radiatus and assessment of mucus-associated bacterial extracts

et al. 2011

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The current study is based on the screening of novel insecticides from new sources that have not being exploited hitherto. The major objectives of this research work were to extract marine molluscs, Lambis lambis, Trochus radiatus and Chicoreus ramosus, from Tuticorin coastal waters using different solvents to test their insecticidal properties and partially purify the active components. The ethyl acetate extracts of L. lambis and T. radiatus showed 100% mortality of Sitophilus oryzae, at a concentration of 200 μg ml −1 . The LC 50 values for ethyl acetate extracts of L. lambis, T. radiatus and C. ramosus were found to be 67.08, 348.86 and 571.42 μg ml −1 , respectively. With regard to bacterial metabolites, at a concentration of 200 μg ml −1 the ethyl acetate extract of A3 was able to elicit an activity of 40% and that of strain A1 -20%. The LC 50 values of the bacterial metabolites were also investigated. Upon chromatographic separation of active ethyl acetate extracts of T. radiatus, the 100% methanol column-purified fraction was found to have an activity of 30% at a concentration of 10 μg against S. oryzae. The purity of the partially pure active compound was observed to be 72.78% on analysis with high pressure thin layer chromatography.

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Streptomyces sp. 173, an insecticidal micro-organism from marine

Cited by 36 publications

References 13 publications

Isolation and characterization of bioactive fungi from shark Carcharodon carcharias’ gill with biopharmaceutical prospects

Isolation and characterization of bioactive fungi from shark Carcharodon carcharias’ gill with biopharmaceutical prospects

Carbon source regulation of antibiotic production

High Performance Thin Layer Chromatography (HPTLC) profile of an insecticidal compound of Trochus radiatus and assessment of mucus-associated bacterial extracts

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