Based on the understanding of China's coal mine production system and the analysis of coal mine comprehensive mining working face safety, combined with a large amount of literature, according to the principles and process of index system construction, using the literature frequency analysis method to construct five primary indicators and 25 secondary indicators of personnel, mechanical equipment, management, environment and information factors, to determine the index system of production system safety evaluation of 5203 comprehensive mining working face of Gaojiayao coal mine The index system was determined. The AHP method was selected to determine the index weights, and the fuzzy comprehensive evaluation method was used to evaluate the safety of the production system of coal mine comprehensive mining working face, to determine the risk status of the working face at the present stage, and to construct a simulation model with the help of a AnyLogic system simulation software to analyze the sensitivity of the indexes, which provides a scientific basis for the safe production and safety management of coal mines and guarantees the safe operation of coal mining and high-quality development of enterprises.