Stress-induced inhibition of sexual behavior: Corticosterone inhibits courtship behaviors of a male amphibian (Taricha granulosa)

Moore, Frank L.; Miller, Laura J.

doi:10.1016/0018-506x(84)90026-6

Cited by 251 publications

(92 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This, combined with our findings, suggests that reward down-regulates corticosterone (but does not necessarily down-regulate anxiety). And our findings are in line with the commonly-accepted view that corticosterone is associated with the suppression of sexual behavior [18][19][20].…”

Section: Discussionsupporting

confidence: 92%

Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model

Yang

Shi²,

Tang

et al. 2016

Neurosci. Bull.

View full text Add to dashboard Cite

To mimic human mood disorders, traditional chronic stresses and social defeat stress have been developed and widely applied. However, these active stresses do not mimic the emotional flaws induced by stresses, and their input levels vary greatly. Also, emotional stresses resulting from social unobtainability remain largely elusive due to the lack of useful animal models. In this study, we developed a mouse model named ''opposite sex contact and isolation'' (OSCI) and found that OSCI induced significant social avoidance, anhedonia, and anxiety. These behavioral defects developed differently after 7 days of OSCI. The social avoidance behavior was self-curable while anxiety gradually worsened but was alleviated by re-pairing with the same female partner. Corresponding to the behavior changes, the plasma corticosterone and phosphorylated cAMP response element binding protein levels were decreased in the nucleus accumbens of the mice that experienced isolation. Together, this study has developed a novel strategy for depression/ anxiety modeling and shows that OSCI may be a useful tool for studying the lovelorn/lovesick type of depression.

show abstract

Section: Discussionsupporting

confidence: 92%

Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model

Yang

Shi²,

Tang

et al. 2016

Neurosci. Bull.

View full text Add to dashboard Cite

show abstract

“…Nongenomic effects of glucocorticoids on behavior have been reported in several species. In rough skinned newts (Taricha granulosa), corticosterone rapidly inhibits male mating behavior (Moore and Miller, 1984), presumably by binding to glucocorticoid receptors positioned at the membrane (Orchinik et al, 1991). Corticosterone also acts rapidly to increase aggression in rats and mice (Poole and Brain, 1974).…”

Section: Discussionmentioning

confidence: 99%

Rapid effects of estradiol on male aggression depend on photoperiod in reproductively non-responsive mice

Trainor

Finy

Nelson

2008

Hormones and Behavior

112

105

View full text Add to dashboard Cite

In three genuses and four species of rodents, housing in winter-like short days (8L:16D) increases male aggressive behavior. In all of these species, males undergo short-day induced regression of the reproductive system. Some studies, however, suggest that the effect of photoperiod on aggression may be independent of reproductive responses. We examined the effects of photoperiod on aggressive behavior in California mice (Peromyscus californicus), which do not display reproductive responsiveness to short days. As expected, short days had no effect on plasma testosterone. Estrogen receptor alpha and estrogen receptor beta immunostaining did not differ in the lateral septum, medial preoptic area, bed nucleus of the stria terminalis, or medial amygdala. However, males housed in short days were significantly more aggressive than males housed in long days. Similar to previous work in beach mice (Peromyscus polionotus), estradiol rapidly increased aggression when male California mice were housed in short days but not when housed in long days. These data suggest that the effects of photoperiod on aggression and estrogen signaling are independent of reproductive responses. The rapid action of estradiol on aggression in short-day mice also suggests that nongenomic mechanisms mediate the effects of estrogens in short days.

show abstract

“…Opiates modulate gonadotropin secretion in mammals (Brooks et al 1986). Adrenal steroids such as corticosterone affect courtship behavior in amphibians (Moore & Miller 1984). What often appear to be effects of testosterone are mediated through the conversion of testosterone to other androgens or estrogens (Callard 1983 (Ciejek et al 1977) (Loumaye et al 1982) Table 1.…”

Section: System Complexity: Sex-steroid Coordination With Other Hormomentioning

confidence: 99%

“…Using the variety of systems acting on the HPG axis, estrogen-mediated behavior, such as lordosis in sexually receptive rats, involves coordination of multiple steroid hormones, neuropeptides and prostaglandins (Sodersten et al 1983;Sirinathsinghji 1984). Similarly, sexual behavior of the male rough-skinned newt Taricha granulosa is regulated by complex endocrine coordination of GnRH-regulated androgenic and estrogenic sex-steroids (Moore 1978;Moore & Miller 1983) together with GnRH, arginine vasotocin (AVT), and melanocyte stimulating hormone (MSH), as well HPA axis components; adrenocorticotropic hormone (ACTH), corticotropin releasing factor (CRF) and the adrenal steroid corticosterone (Moore et al 1982;Moore & Miller 1984). The evolution of complex coordination may offer finer appropriation of sex-steroid mediated behavioral responses to complex, nuanced or varied stimuli, and may allow robustness of important behaviors when uncoupled from what may once have been key regulators (Crews & Moore 1986;Moore 1987).…”

Section: System Complexity: Sex-steroid Coordination With Other Hormomentioning

confidence: 99%

“…Much of this variation may be related to the physiological stage of the animal at the time of exposure (reviewed in Hayes (1998). Sex steroid effects on amphibian rates of metamorphosis (Sluczewski & Roth 1950) as well as adrenal steroid effects on courtship behavior (Moore & Miller 1984) and gonadal differentiation (Hayes 1998) are reflective of high levels of cross-connectivity between HPG, HPA and HPT systems (Hayes et al 1993). Developmental timing can vary dramatically between closely related species (Buchholz & Hayes 2000), and differences in developmental timing may affect ages or stages when animals have achieved the organizational capacity to exhibit hormone-induced effects (Hayes 1997a).…”

Section: Amphibians (Http://tolweborg/amphibia)mentioning

confidence: 99%

See 1 more Smart Citation