Stroke as an early manifestation of systemic lupus erythematosus.

Chin, D; Zilko, P. J.

doi:10.1136/jnnp.46.7.688-b

Cited by 3 publications

(2 citation statements)

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“…Consequently, 10 articles were finalized that reported on cases of SLE with ischemic stroke as the initial presentation, documenting a total of 17 cases. [3][4][5][6][7][8][9][10][11][12] Adding the three cases presented in this study, a total of 20 cases with ischemic stroke as the initial manifestation of SLE were included. Among these cases, there were 6 males and 14 females, with ages ranging from 16 to 55 years.…”

Section: Review Of the Literaturementioning

confidence: 99%

“…Among them, 9 studies were excluded as they focused on stroke occurrence post‐SLE diagnosis. Consequently, 10 articles were finalized that reported on cases of SLE with ischemic stroke as the initial presentation, documenting a total of 17 cases 3–12 . Adding the three cases presented in this study, a total of 20 cases with ischemic stroke as the initial manifestation of SLE were included.…”

Section: Review Of the Literaturementioning

confidence: 99%

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Three cases of systemic lupus erythematosus presenting with ischemic stroke as the initial symptom: Case reports and literature review

Li,

Liu,

et al. 2024

Immunity Inflam & Disease

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BackgroundIschemic stroke constitutes a grave complication within the context of systemic lupus erythematosus (SLE), typically manifesting several years postdiagnosis of SLE. Incidents where ischemic stroke precedes and acts as an initial symptom of SLE are comparatively rare in its early stages, and such presentations are frequently misdiagnosed as ischemic cerebrovascular diseases, posing significant diagnostic challenges.Case ReportsThis article presents three cases of young females in whom ischemic stroke emerged as the initial manifestation of SLE. It incorporates a review of 17 case reports published over the past two decades, focusing on patients with SLE where ischemic stroke was a primary symptom. This discussion encompasses the clinical presentation, outcomes, and therapeutic approaches for these patients.ConclusionIn young patients, particularly females presenting with ischemic stroke and especially in cases accompanied by hematologic or multisystemic involvement, there should be heightened vigilance for SLE‐induced ischemic stroke. Early diagnosis and treatment significantly enhance patients' quality of life and survival rates.

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