Structural and biochemical alterations during the healing process of tendons treated with Aloe vera

Aro, Andréa Aparecida de; Nishan, Umar; Perez, M.O.; Rodrigues, Rodney Alexandre Ferreira; Foglio, Mary Ann; Carvalho, João Ernesto de; Gomes, Luiz Fernando; Vidal, Benedicto de Campos; Pimentel, Edson Rosa

doi:10.1016/j.lfs.2012.09.002

Cited by 29 publications

(28 citation statements)

References 69 publications

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“…MMP-9 diminished 14 after lesion and the active isoform of MMP-2 increased on day 21 in plant-treated groups. The present study indicates a beneficial effect of Aloe vera in the tissue reorganization in the transected region of the tendon 21 days after injury and is supported by an increase of active MMP-2 [73] .…”

Section: Stimulation Of Periodontal Fibroblasts and Bone Formationsupporting

confidence: 76%

Putative Prophylaxes of Aloe Vera for Age-Related Diseases

Yagi

2015

Journal of Gastroenterology and Hepatology Research

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The aim of the present review is focused on putative prophylaxes of Aloe vera for age-related diseases, and its check items are generally known traditional and specific diseases followed by In vitro, animal, and preliminary clinical studies: (1) prevention of cancer and alleviation of progeria; (2) prevention of cardiovascular and cerebro-vascular disorders, and inhibition of acetylcholinesterase; (3) preliminary clinical study of an aloemannose multinutrient complex on cognitive and immune functioning in Alzheimer's disease; (4) prevention of photo-aging and polycystic ovarian syndrome; (5) stimulation of periodontal fibroblasts, bone formation, and healing of pain and nephro-toxicity; and (6) anti-inflammation and immuno-response, excluding diabetic and hepatic disorders.

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Section: Stimulation Of Periodontal Fibroblasts and Bone Formationsupporting

confidence: 76%

Putative Prophylaxes of Aloe Vera for Age-Related Diseases

Yagi

2015

Journal of Gastroenterology and Hepatology Research

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“…MMP-9 diminished 14 days after lesion and the active isoform of MMP-2 increased on day 21 in plant-treated groups. Significance: The present study indicates a beneficial effect of Aloe vera in the tissue reorganization in the transected region of the tendon 21 days after injury and is supported by an increase of active MMP-2 [79] .…”

Section: Born Formation (Born Marrow Stromal Cells) and Humoral Immunsupporting

confidence: 57%

Putative Prophylaxes Updated of Placenta Extract and Aloe vera as Biogenic Stimulants

Yagi

Ataka

2014

Journal of Gastroenterology and Hepatology Research

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Gastroenterology and Hepatology Researchdation, and the possible putative prophylaxes to optimize cognitive decline in older adults with pre-diabetes symptom. Because of the diversities of placental extract and Aloe vera as biogenic stimulants, present review introduced the briefly selected authors' intentions in each topical subject. Specially, the influence of gut microbiota to host is astonishing and highlighting that the consequence of our behaviours affect not only the environment without, but also that within us. Based on geriatric and neurological viewpoint, present review highlights current therapeutic strategies of placenta extract and Aloe vera as the so-called "biogenic stimulants", aimed at producing a biological rejuvenator in placental extract and improving cognitive function via modifying the brain's insulin sensitivity in Aloe vera.

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“…MMPs are generally activated by other proteinases. Activation of MMPs is commonly observed in pathological cases (44)(45)(46)(47). High activity of the active MMP-2 isoform was found in G3 compared with G1.…”

Section: Discussionmentioning

confidence: 99%

“…However, in this study, positive changes were observed when GT was administered together with a glycine diet. Our group has searched for different therapies, such as the use of a low level laser (8,51), electroacupuncture (45) and plant extracts (46,57), to improve the structure of the Achilles tendon, considering biochemical and structural elements after partial rupture. These alternatives mainly aim to accelerate tissue healing because the tendon shows low vascularity and cellularity, which directly influences the tissue remodeling and recovery time.…”

Section: Discussionmentioning

confidence: 99%