2021
DOI: 10.3390/ma14040712
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Structural and Material Determinants Influencing the Behavior of Porous Ti and Its Alloys Made by Additive Manufacturing Techniques for Biomedical Applications

Abstract: One of the biggest challenges in tissue engineering is the manufacturing of porous structures that are customized in size and shape and that mimic natural bone structure. Additive manufacturing is known as a sufficient method to produce 3D porous structures used as bone substitutes in large segmental bone defects. The literature indicates that the mechanical and biological properties of scaffolds highly depend on geometrical features of structure (pore size, pore shape, porosity), surface morphology, and chemi… Show more

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Cited by 53 publications
(23 citation statements)
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References 247 publications
(325 reference statements)
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“…Both the Ti-6Al-4V and Ti-13Nb-13Zr alloys have a modulus of elasticity similar to that of human bone. Additional modifications of the surface of titanium alloys enable appropriate osseointegration [ 24 , 25 ].…”
Section: Introductionmentioning
confidence: 99%
“…Both the Ti-6Al-4V and Ti-13Nb-13Zr alloys have a modulus of elasticity similar to that of human bone. Additional modifications of the surface of titanium alloys enable appropriate osseointegration [ 24 , 25 ].…”
Section: Introductionmentioning
confidence: 99%
“…The first coating may be then considered in such applications in which the coating opposes high stresses and must be resistant to wear or cracking. The second coating, which includes antibacterial metal, can be recommended for particular coatings that should actively kill bacteria in their neighborhood [56], but with no excessive loads during surgery and further use of the implant.…”
Section: Discussionmentioning
confidence: 99%
“…Gupta et al (2021) studied the tensile behavior of EBMed Ti64 alloy and resulted that the tensile strength is highly affected by the strain rate and temperature whereas the existence of micro-cracks reduces the tensile strength and ductility. As the mechanical properties of bone depend on age, activity and disease status, therefore proper matching of elastic modulus constitutes a major challenge for tissue engineering (Dziaduszewska and Zieli nski, 2021). The desired mechanical properties in Pure Ti can be achieved by the addition of alloying with the help of alloying elements such as Nb, Zr, Sn and Ta.…”
Section: Mechanical Propertiesmentioning
confidence: 99%