Zinc oxide nanoparticles with PVA were used as additives for improving the specifications of the Iraqi dyes produced in the Modern Paints Company) D-5800 SFFA, epoxy for the inside drinking water tanks, D-5547 A-9101, lead food epoxy D-5544SFA-12 and transparent food epoxy primer (G-5900) that suffer from poor adhesion, peeling ability and decreasing in biological activity after a period of time, as the following: 4g of PVA was dissolved in 100mL of deionized water (DI) using a magnetic stirrer for 1 hour at 60°C, followed by the addition of 0.6g of ZnO NPs with a stirrer for 1 hour at 60°C. The temperature of this solution was allowed to drop to room temperature. Other samples were also prepared in the same way, using ZnO and TiO2 in a 1:1 ratio. The included, the tests for adhesion ability, biological effectiveness and time-acceleration weathering of the coating were carried out. Experimental results on a gypsum (Bork) piece coated with nano-coating over a period of more than six months showed an increase in adhesion ability of over 160% for some samples, along with an increase in biological activity, such as (E. coli and ST aureuse).