1979
DOI: 10.3109/00016487909137158
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Structural Changes in the Organ of Corti of the Guinea Pig after Obstruction of the Arterial Blood Flow to the Inner Ear

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Cited by 11 publications
(5 citation statements)
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“…10 The inner ear receives blood supply from the labyrinthine artery; temporary stasis of leukocytes is sufficient to cause permanent damage to the delicate inner ear structures. 11 In our patient, the white blood cell count findings supported the diagnosis of leukostasis. Notably, CNS infiltration can be successfully treated by CNS-directed chemotherapy followed by allogenetic stem cell transplantation, whereas sensorineural hearing loss does not respond to this therapy.…”
Section: Discussionsupporting
confidence: 73%
“…10 The inner ear receives blood supply from the labyrinthine artery; temporary stasis of leukocytes is sufficient to cause permanent damage to the delicate inner ear structures. 11 In our patient, the white blood cell count findings supported the diagnosis of leukostasis. Notably, CNS infiltration can be successfully treated by CNS-directed chemotherapy followed by allogenetic stem cell transplantation, whereas sensorineural hearing loss does not respond to this therapy.…”
Section: Discussionsupporting
confidence: 73%
“…The labyrinthine artery is responsible for supplying the cochlea and vestibular apparatus with blood, and even temporary stasis can cause irreversible damage to the delicate neuronal and vascular structures of the inner ear. 24 As histologic studies are the only way to confirm the etiology of the patient's otologic symptoms, we cannot be certain of the cause. However, given the extreme hyperleukocytosis with WBC of 685 000/µL, a diagnosis of leukostasis seems reasonable.…”
Section: Discussionmentioning
confidence: 99%
“…The labyrinthine artery is responsible for supplying the cochlea and vestibular apparatus with blood, and even temporary stasis can cause irreversible damage to the delicate neuronal and vascular structures of the inner ear. 24…”
Section: Discussionmentioning
confidence: 99%
“…Because the internal auditory artery is the final artery, the cochlea is considered susceptible to ischemia due to VBI and occlusive disease [8,32,[67][68][69][70]. VBI is sometimes associated with hearing loss and/or tinnitus [33][34][35][36][37][38][39][40]62,71,72].…”
Section: Hearing Loss Due To Vertebrobasilar Artery Insufficiencymentioning
confidence: 99%