Structural characteristics of the dorsomedial nucleus of the cat thalamus

Babmindra, V. P.; Bragina, T. A.; Khokhryakova, I. M.

doi:10.1007/bf01185053

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…1979). Also, Golgi-type II neurons that send their axons outside the thalamus were reported in the mediodorsal (MD) nucleus (Babmindra et al 1977). The type II neurons in the human AV nucleus were found to have grape-like dendritic appendages not only at the dendritic shafts but also at dendritic tips.…”

Section: Discussionmentioning

confidence: 99%

Neuronal Types in the Human Anterior Ventral Thalamic Nucleus: A Golgi Study

2007

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Neurons in the anterior ventral (AV) thalamic nucleus of human adults were impregnated by Golgi-Kopsch impregnation method. Results showed that at least three morphological types of neurons could be recognized in the human AV thalamic nucleus. Type I neurons were medium to large with rich dendritic arborization. Both tufted and radiating dendritic branching patterns were seen in almost every neuron of this type. Only the initial axonal segments of these cells were impregnated suggesting that these axons were heavily myelinated. Type II neurons were medium in size with poor to moderate dendritic arborization. Many of these cells possess a few dendritic grape-like appendages. Long segments (up to 300 microm) of their axons were impregnated suggesting that these axons were either unmyelinated or thinly myelinated. These axons change their direction and form loops very often. No local branches were seen for these axons suggesting that they could be projection axons. Type III neurons were small with only one or two dendrites with poor arborization. No axons for these cells were seen in this study. The three neuronal types in the human AV thalamic nucleus were compared with neuronal types already described in other thalamic nuclei of human and non-human species. The results of this study might provide a morphological basis for further electrophysiological and / or pathological studies.

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Section: Discussionmentioning

confidence: 99%

Neuronal Types in the Human Anterior Ventral Thalamic Nucleus: A Golgi Study

2007

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Neuronal and synaptic composition of the mediodorsal thalamic nucleus in the rat: A light and electron microscopic golgi study

Kuroda

López‐Mascaraque

Price

1992

J of Comparative Neurology

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The distribution and dendritic domain of neurons in each segment of the mediodorsal thalamic nucleus (MD) have been studied in the rat with the Golgi technique. In addition, a combined Golgi method‐electron microscopic (Golgi‐EM) study was undertaken to determine the distribution of morphologically distinct synapse types along the dendrites of individual identified neurons in MD. All the subdivisions or “segments” of MD (medial, central, lateral) contained both stellate and fusiform cells. The dendritic domain of both types of cells was predominantly restricted to the same segment of MD that contained the cell body of the neuron. Typical stellate neurons were found near the center of each segment, with radiating dendrites that extended to but not across the boundaries of the segment. Fusiform cells were usually located close to the segmental or nuclear boundaries and tended to have dendrites oriented parallel to those borders; again, the dendrites tended not to extend across borders between segments or at the outer edge of MD. In the medial segment of MD many fusiform cells had especially bipolar dendritic configurations, generally with a dorsoventral orientation. Because no small neurons were identified that might correspond to thalamic interneurons, all the impregnated cells in MD are presumed to be thalamocortical projection neurons. These results indicate that cells and their major dendrites are confined to a single segment of MD, with little dendritic overlap across segmental or nuclear borders. The segments of MD may therefore be considered to be relatively independent subnuclei. The distribution of the four types of synapses previously identified in MD (Kuroda and Price, J. Comp. Neurol., 303:513–533, 1991) was determined along several identified dendrites studied with the Golgi‐EM method. Primary dendrites were contacted mostly by large axon terminals, including both large, round vesicle (LR) terminals and large, pleomorphic vesicle (LP) terminals, as well as a few small to medium sized terminals with pleomorphic vesicles (SMP). No small terminals with round vesicles (SR terminals) were observed to make synapses with primary dendrites. Secondary and tertiary dendrites received synapses from all types of axon terminals. Higher order dendrites were contacted predominantly by SR boutons, but they also carried some LR and SMP terminals. In addition, SMP boutons were often found to form symmetric contacts with cell somata. © 1992 Wiley‐Liss, Inc.

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Circuit-based Localization of Ferret Prefrontal Cortex

Duque

McCormick

2009

Cerebral Cortex

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We examined the extent of the ferret prefrontal cortex (PFC) and its reciprocal connections with the mediodorsal nucleus of the thalamus (MD) by anterograde and retrograde labeling in 6- to 14-week-old male ferrets. Our results indicate that in the ferret, as in other species, MD projects heavily to the PFC although it also projects to other cortical and subcortical structures. The MD projection to PFC terminates largely in layer IV with lighter innervation of layers II, III, V, and VI. The cells projecting back to MD are mostly in layer VI. The parvocellular component of MD projects to and receives projections from the more caudal and dorsomedial component of the PFC, whereas the magnocellular portion of MD projects to and receives projections from the more rostral and lateral component of the PFC. With these results we have localized the ferret PFC, defined as a frontal cortical region with heavy reciprocal connections with the MD.

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Structural characteristics of the dorsomedial nucleus of the cat thalamus

Cited by 3 publications

References 2 publications

Neuronal Types in the Human Anterior Ventral Thalamic Nucleus: A Golgi Study

Neuronal Types in the Human Anterior Ventral Thalamic Nucleus: A Golgi Study

Neuronal and synaptic composition of the mediodorsal thalamic nucleus in the rat: A light and electron microscopic golgi study

Circuit-based Localization of Ferret Prefrontal Cortex

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