Structural characterization of phenolic antioxidants from purple perilla (Perilla frutescens var. acuta) leaves

Jun, Hyun-Il; Kim, Beom‐Tae; Song, Geun-Seoup; Kim, Youngsoo

doi:10.1016/j.foodchem.2013.10.028

Cited by 86 publications

(75 citation statements)

References 25 publications

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“…Several studies describe the use of NMR in the identification of diff fi erent ff ff compounds present in natural matrices: epimeric forms of fl avone glycosides fl [219]; tannin isomers [220]; anthocyanins [221]; rosmarinic acid [222]; para-hydroxy methyl benzoate glucoside, cycloeucalenol cis-ferulate, cycloeucalenol trans-ferulate, trans-ferulic acid, trans-ferulic acid methyl ester, cis-ferulic acid, cis-ferulic acid methyl ester, methyl caffeate, vanillic ff ff aldehyde and para-hydroxy benzaldehyde [223]; 9-O-(3-carboxymethyl-4-(p-formylstyryl))hydroxybutanoic acid, 2-hydroxy-3-methoxycaffeic ff ff acid 5-O-β-D-glucopyranoside and 3 -O-methyl-4 -O-(4-O-galloyl-α-Lrhamnopyranosyl) ellagic acid [224].…”

Section: Structure Elucidation Of Individual Antioxidant Compoundsmentioning

confidence: 99%

Determination of Antioxidant Compounds in Foodstuff

et al. 2016

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Section: Structure Elucidation Of Individual Antioxidant Compoundsmentioning

confidence: 99%

Determination of Antioxidant Compounds in Foodstuff

et al. 2016

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“…Activity Natural antioxidant is considered superior to synthetic as it is safe and produces a prominent action, especially plant phenolics, flavonoids, tannins and anthocyanidins [10]. Herein, we presented antioxidant activity of stilbene compounds from methanol extract of pigeon pea (C. cajan (L.) Millsp.…”

Section: Introductionmentioning

confidence: 99%

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

2018

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New Prenylated stilbene derivatives, 3-hydroxy-4-prenyl-5-methoxy-stilbene acid (1) and 5,4'-dihydroxy-3-methoxy-2-prenyl-stilbene (2) Millsp.; stilben terprenilasi; antioksidan;2, ABSTRAK Dua turunan stilben terprenilasi baru, Asam 3-hidroksi-4-prenil-5-metoksi-stilben (1) dan 5,4'-dihidroksi-3-metoksi-2-prenil-stilben (2) telah berhasil diisolasi dari ekstrak metanol tumbuhan kacang kayu (Cajanus cajan (L.) Millsp.) anggota famili fabaceae. Tujuan penelitian ini adalah untuk mengetahui potensi senyawa-senyawa tersebut sebagai antioksidan secara in vitro menggunakan radikal 2,2-difenil-1-pikrihidrazil (DPPH

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“…acuta is a traditional medicinal plant used in Asian countries, including Korea, China, and Japan, for treating symptoms such as depression, anxiety, allergies, bacterial and fungal infections, common cold, shivering fits, fever, chest pains, and cough [21,22,23]. The leaves of this plant are widely consumed in sushi, soups, and salads, as a spice and food colorant, and for garnishing [24]. Previous pharmacological studies have shown that P. frutescens var.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, studies have reported that flavonoids, phenolic acids, and anthocyanins were isolated from the leaves of P. frutescens [29]. Phenolic compounds in this plant extracts exhibit high antioxidant activity [24]. However, the effect of these compounds on visual fatigue has not yet been elucidated.…”

Section: Introductionmentioning

confidence: 99%

Amelioration of Visual Display Terminal-induced Ocular Fatigue by Aqueous Extracts of <i>Perilla frutescens </i>var. acuta

Kim¹,

Choi²,

Kim³

et al. 2017

JFNR

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In this study, we investigated the effects of Perilla frutescens var. acuta aqueous extract (PFA) on eyestrain using in vitro, ex vivo, and clinical tests. We confirmed the antioxidant activity of compounds present in the extract by using high-performance liquid chromatography. PFA contains antioxidant compounds such as rosmarinic acid, luteolin-7-O-glucuronide, and apigenin-7-O-glucuronide, and has been shown to inhibit reactive oxygen species generation in C2C12 muscle cells. In an ex vivo study, PFA inhibited the carbachol (100 μM)-induced contraction of ciliary muscle from rabbit eyeball. We then investigated the mechanism by which PFA caused muscle relaxation and found that it effectively increased cyclic GMP production and inhibited PDE5A activity, but did not affect the cyclic AMP pathway, in cultured human aortic smooth muscle cells. In addition, PFA (50, 100, and 200 µg/mL) dose-dependently decreased basal intracellular calcium in smooth muscle cells and attenuated the endothelin-1-stimulated increase in intracellular calcium. Finally, we performed a clinical study to evaluate the effects of PFA on the near point of accommodation (NPA) after visual display terminal (VDT) work. Thirty participants were randomized to either PFA (500 mg/day) or placebo, and intake for one consecutive week. NPA was evaluated before and after 2 h of VDT work, and was found to be improved in the PFA-treated group. Thus, our findings show that PFA may ameliorate visual fatigue.

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Structural characterization of phenolic antioxidants from purple perilla (Perilla frutescens var. acuta) leaves

Cited by 86 publications

References 25 publications

Determination of Antioxidant Compounds in Foodstuff

Determination of Antioxidant Compounds in Foodstuff

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

Amelioration of Visual Display Terminal-induced Ocular Fatigue by Aqueous Extracts of <i>Perilla frutescens </i>var. acuta

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