2022
DOI: 10.3390/antiox11091635
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Structural Elucidation of Novel Stable and Reactive Metabolites of Green Tea Catechins and Alkyl Gallates by LC-MS/MS

Abstract: Synthetic gallic acid derivatives are employed as additives in food, personal care products, and pharmaceutical formulations. Despite their widespread use, little is known about their human exposure, health effects, and metabolism. Green tea catechins are natural antioxidants, known for their health-promoting properties, and are also employed as food additives or in personal care products. The objective of this study was to establish metabolic pathways involved in the biotransformation of green tea catechins a… Show more

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Cited by 9 publications
(5 citation statements)
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“…[ [24][25][26][27][28][29][30][31][32][33][34][35] Extract of dried leaves Main compounds: catechins, polyphenols, or flavan-3-ols. [64,65] EGCG (65% of total catechins) depending on drying conditions and extraction process. [65,66] Extraction of Catechins with polar organic solvents OR Good extraction but unusable for cosmetics.…”
Section: Discussionmentioning
confidence: 99%
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“…[ [24][25][26][27][28][29][30][31][32][33][34][35] Extract of dried leaves Main compounds: catechins, polyphenols, or flavan-3-ols. [64,65] EGCG (65% of total catechins) depending on drying conditions and extraction process. [65,66] Extraction of Catechins with polar organic solvents OR Good extraction but unusable for cosmetics.…”
Section: Discussionmentioning
confidence: 99%
“…[64,65] EGCG (65% of total catechins) depending on drying conditions and extraction process. [65,66] Extraction of Catechins with polar organic solvents OR Good extraction but unusable for cosmetics. Pharmacomodulations to increase the stability and bioavailability Alkylated gallate esters, which retain very good antioxidant power and better bioavailability but have shown cytotoxicity in rats.…”
Section: Discussionmentioning
confidence: 99%
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