Structural Investigation of Resin Glycosides from <i>Ipomoea lonchophylla</i>

MacLeod, John K.; Ward, A. David; Oelrichs, Peter B.

doi:10.1021/np960693q

Cited by 25 publications

(25 citation statements)

References 18 publications

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“…One fraction from I. lonchophylla was toxic to mice but no tests have so far been carried out to determine whether this toxic fraction contribute to intoxication and death among newly born lambs. The toxic fraction contained an inseparable mixture of resin glycosides (Macleod et al, 1997).…”

Section: Ipomoea Lonchophylla Jm Blackmentioning

confidence: 99%

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Meira¹,

Silva²,

David³

et al. 2012

Rev. bras. farmacogn.

170

120

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Approximately 600-700 species of Ipomoea, Convolvulaceae, are found throughout tropical and subtropical regions of the world. Several of those species have been used as ornamental plants, food, medicines or in religious ritual. The present work reviews the traditional uses, chemistry and biological activities of Ipomoea species and illustrates the potential of the genus as a source of therapeutic agents. These species are used in different parts of the world for the treatment of several diseases, such as, diabetes, hypertension, dysentery, constipation, fatigue, arthritis, rheumatism, hydrocephaly, meningitis, kidney ailments and infl ammations. Some of these species showed antimicrobial, analgesic, spasmolitic, spasmogenic, hypoglycemic, hypotensive, anticoagulant, anti-infl ammatory, psychotomimetic and anticancer activities. Alkaloids, phenolics compounds and glycolipids are the most common biologically active constituents from these plant extracts.

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Section: Ipomoea Lonchophylla Jm Blackmentioning

confidence: 99%

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Meira¹,

Silva²,

David³

et al. 2012

Rev. bras. farmacogn.

170

120

View full text Add to dashboard Cite

show abstract

“…This plant is used in Portuguese traditional medicine to cure hydropsy, paralysis, rheumatism, and scurvy [77]. (81) has been isolated from the aerial parts of Australian plant Ipomoea lonchophylla [78]. Many species of Ipomoea were and still are used in folk medicine in different parts of the world [79].…”

Section: Formation Of Fatty Acid Glucuronides 16 ± 18 In Human Livermentioning

confidence: 99%

Chemistry and Biod iversity of the Biologically Active Natural Glycosides

Dembitsky¹

2004

Chemistry & Biodiversity

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“…Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in traditional medicine for the treatment of infl ammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems (Fosberg & Sachet, 1977). Pharmacological studies on extracts of many species of Ipomoea have reported anti-infl ammatory, antimicrobial, analgesic, spasmogenic, anti-spasmolytic, hypotensive, psychotomimetic and anticancer effects (MacLeod et al, 1997). Chemical investigations have shown that indole alkaloids and resin glycosides are the most common biologically active constituents in the Convolvulaceae (Noda et al, 1994;Noda et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Anti-oxidative and anti-ulcerogenic activity of Ipomoea imperati

Miyahara¹,

Imamura²,

Freitas

et al. 2011

Rev. bras. farmacogn.

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Abstract:Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in traditional medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains and stomach problems. This work evaluates the anti-oxidative activity by ESR (Electron Spin Resonance spectroscopy) and the preventive and curative actions of I. imperati in gastric ulcer animal model. Ipomoea imperati (200 mg/kg, p.o.) prevented the formation of gastric lesions in 78% (p<0.05) when compared with the negative control tween 80. Lanzoprazole, prevented in 85% the gastric lesions formation induced by ethanol (p<0.05). Therefore, the oral administration of I. imperati one hour before the ulcerogenic agent prevented the ulcer formation, conserving the citoprotection characteristics of the gastric mucosa and assuring the integrity of gastric glands and gastric fossets. The healing activity of I. imperati (200 mg/kg, p.o.) evaluated in chronic ulcer experiments induced by the acetic acid, was 72% (p<0.05). The positive control, ranitidine, healed 78% of the gastric lesions (p<0.05). The histological analysis confirmed the recovery of the mucosal layer and the muscle mucosal layer harmed by the acetic acid. Experiments in vitro with DPPH (2.2-diphenyl-1-picrylhydrazyl) of anti-oxidative activity demonstrated that I. imperati presents an IC50 of 0.73±0.01 mg/mL.

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Structural Investigation of Resin Glycosides from Ipomoea lonchophylla

Cited by 25 publications

References 18 publications

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Chemistry and Biod iversity of the Biologically Active Natural Glycosides

Anti-oxidative and anti-ulcerogenic activity of Ipomoea imperati

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