2020
DOI: 10.1094/mpmi-02-20-0028-r
|View full text |Cite
|
Sign up to set email alerts
|

Structural Requirements of the Phytoplasma Effector Protein SAP54 for Causing Homeotic Transformation of Floral Organs

Abstract: Phytoplasmas are intracellular bacterial plant pathogens that cause devastating diseases in crops and ornamental plants by the secretion of effector proteins. One of these effector proteins, termed SECRETED ASTER YELLOWS WITCHES’ BROOM PROTEIN 54 (SAP54), leads to the degradation of a specific subset of floral homeotic proteins of the MIKC-type MADS-domain family via the ubiquitin-proteasome pathway. In consequence, the developing flowers show the homeotic transformation of floral organs into vegetative leaf-l… Show more

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

0
13
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 10 publications
(14 citation statements)
references
References 67 publications
0
13
0
Order By: Relevance
“…Stolbur phytoplasma infected tomato showed virescence, phyllody, sepal hypertrophy, and aborted reproductive organs ( Pracros et al, 2006 ). Expressing SAP54, an effector of Aster Yellows phytoplasma strain Witches’ Broom (AY-WB), was sufficient to induce phyllody in Arabidopsis ( Aurin et al, 2020 ). Further studies showed that SAP54 alters the host plant reproductive and floral development by degrading a group of type II MADS-domain transcription factors (MTFs) regulating the floral transition and floral organ development ( Jagdale et al, 2021 ).…”
Section: Altering Host Growth and Development As A Virulence Strategymentioning
confidence: 99%
See 1 more Smart Citation
“…Stolbur phytoplasma infected tomato showed virescence, phyllody, sepal hypertrophy, and aborted reproductive organs ( Pracros et al, 2006 ). Expressing SAP54, an effector of Aster Yellows phytoplasma strain Witches’ Broom (AY-WB), was sufficient to induce phyllody in Arabidopsis ( Aurin et al, 2020 ). Further studies showed that SAP54 alters the host plant reproductive and floral development by degrading a group of type II MADS-domain transcription factors (MTFs) regulating the floral transition and floral organ development ( Jagdale et al, 2021 ).…”
Section: Altering Host Growth and Development As A Virulence Strategymentioning
confidence: 99%
“…Arabidopsis radiation-sensitive-23 (RAD23) family proteins, RAD23C, and RAD23D, physically interact with SAP54 and are required for the degradation of host MTFs and phytoplasma-induced phyllody ( MacLean et al, 2014 ). Aster leafhopper Macrosteles quadrilineatus has oviposition preference for plants with green leaf-like flowers induced by SAP54 ( MacLean et al, 2011 ; Aurin et al, 2020 ). It is proposed that SAP54-induced phyllody facilitates the transmission of AY-WB.…”
Section: Altering Host Growth and Development As A Virulence Strategymentioning
confidence: 99%
“…Phytoplasmas are small bacterial plant pathogens that are transmitted by phloem-feeding insects ( 1 , 2 ). Phytoplasmas lack many basic metabolic pathways and thus rely on the host to complete their life cycle and release virulence effectors into plants, causing drastic changes in cell architecture, the defense response, and volatile production ( 3 , 4 , 5 , 6 , 7 ). It is now known that in a variety of plants, phytoplasma infestation has adverse effects on fruits, seeds, and morphology, manifesting as yield loss in wheat, lack of fruit bearing by jujube plants, and decreased quality of paulownia trees ( 8 , 9 , 10 , 11 ).…”
mentioning
confidence: 99%
“…The conserved amino acid residues at positions 64 and 30 in the phyllogen family play a key and minor role, respectively, in leaf induction ( 25 ). Pro substitutions at the 27th, 65th, and 69th amino acid positions in the putative turn region of SAP54 resulted in failure in interaction with MADS-box TFs, and the protein lost the ability to induce homeotic transformation of floral organs, but Ala substitution had no effect ( 6 ). Deletion of the C-terminal CC domain and nuclear localization signal of SWP1 could not induce witches’ broom, and deletion of the C-terminal CC domain alone inhibited BRC1 degradation, indicating that the nuclear localization signal and the CC domain are required for the function of SWP1 ( 17 ).…”
mentioning
confidence: 99%
See 1 more Smart Citation