Structural Transition-Induced Raman Enhancement in Bioinspired Diphenylalanine Peptide Nanotubes

Abstract

Semiconducting materials are increasingly proposed as alternatives to noble metal nanomaterials to enhance Raman scattering. We demonstrate that bioinspired semiconducting diphenylalanine peptide nanotubes annealed through a reported structural transition can support Raman detection of 10–7 M concentrations for a range of molecules including mononucleotides. The enhancement is attributed to the introduction of electronic states below the conduction band that facilitate charge transfer to the analyte molecule. These results show that organic semiconductor-based materials can serve as platforms for enhanced Raman scattering for chemical sensing. As the sensor is metal-free, the enhancement is achieved without the introduction of electromagnetic surface-enhanced Raman spectroscopy.

Organic–inorganic hybrid ferrocene/AC as cathodes for wide temperature range aqueous Zn-ion supercapacitors

“…50 Aer cycling, the C-C peak appears at 284.8 eV, 10,51 and the lowest energy peak of 282.4 eV is attributed to environmental contamination. 52 Fig. 5e shows C 1s spectrum of ferrocene/AC cathode before and aer cycling.…”

Material design, development, and trend for surface-enhanced Raman scattering substrates

“…5C). 167 Apart from small molecular organic semiconductors, a few semiconductive organic substrates, includ-ing π-conjugated polymers 168,169 and peptide nanotubes, 170 are also reported.…”

Thermally‐controlled spherical peptide gel architectures prepared using the pH switch method

“…The enhancement is attributed to the introduction of electronic states below the conduction band that facilitate charge transfer to the analyte molecule. [ 29 ] Thus, in this study, we have investigated the influence of both temperature and water content on Fmoc‐FF gel formation. We have found that microsphere formation can be tuned by increasing the water content and by heating the solution.…”