Structure and absolute configuration of (E)-(–)-2-cyclododecenyl camphanate

Abstract

Abstract. C22H3404, Mr=362.51, monoclinic, P2~, a= 7.371 (I), b= 10.571 (1), c= 13.538 (2)A, t= 90.36 (1) °, V= 1054.84 A 3, Z = 2, D x = 1. 141 Mg m -3, 2(Cu Kot) = 1.5418 A, p = 0.577 mm -~, F(000) = 396, T= 296 K, R = 0.057 for 1550 unique reflections with I>_a(1). The crystal conformation of the 12-membered ring in the title compound and its absolute configuration (1R) have been determined. The ring adopts a conformation with a necessarily approximate twofold axis in the crystal but it appears to be highly flexible. Introduction.As part of an ongoing study of the relation of the configuration and conformation of medium-ring 2-cycloalkenyl p-bromobenzoates with their chiroptical properties, we prepared a sample of (E)-2-cyclododecanol. Earlier studies by Ito, Kasai,

1,2,6-Trimethyl-3,5-nonamethylenepyridinium perchlorate. Crystal structure and molecular mechanics calculations for ansa-[9]-meta-cyclophanes

“…The same great mobility was encountered previously in the crystal structure of (E)-(-)-2-cyclododecenyl camphanate, which is also loosely packed. 4 However, the torsion angles are quite different in this case due to the trans double bond, which is a different structural element as compared to our meta-cyclophanic unit.…”