Structure-dependent photothermal anticancer effects of carbon-based photoresponsive nanomaterials

Miao, Wenjun; Shim, Gayong; Lee, Soondong; Oh, Yu‐Kyoung

doi:10.1016/j.biomaterials.2014.01.043

Cited by 60 publications

(28 citation statements)

References 30 publications

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“…These studies demonstrate an increased retention time for the high aspect ratio NMs, which may lead to increased toxicity (Donaldson et al 2013a, Murphy et al 2013. Similarly, the bio-distribution of differently shaped carbon-based NMs has demonstrated that nano-graphene sheets circulate and are retained in the blood for twice as long as fibre-shaped CNTs (Miao et al 2014).…”

Section: Discussionmentioning

confidence: 97%

Nanomaterial translocation–the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs–a review

Kermanizadeh

Balharry

Wallin

et al. 2015

Critical Reviews in Toxicology

141

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Engineered nanomaterials (NMs) offer great technological advantages but their risks to human health are still not fully understood. An increasing body of evidence suggests that some NMs are capable of distributing from the site of exposure to a number of secondary organs. The research into the toxicity posed by the NMs in these secondary organs is expanding due to the realisation that some materials may reach and accumulate in these target sites. The translocation to secondary organs includes, but is not limited to, the hepatic, central nervous, cardiovascular and renal systems. Current data indicates that pulmonary exposure is associated with low (inhalation route-0.00001-1% of total applied dose-24 h) translocation of virtually insoluble NMs such as iridium, carbon black, gold and polystyrene, while slightly higher translocation has been observed for NMs with either slow (e.g., silver, cerium dioxide and quantum dots) or fast (e.g., zinc oxide) solubility. The translocation of NMs following intratracheal, intranasal and pharyngeal aspiration is higher (up to 10% of administered dose), however the relevance of these routes for risk assessment is questionable. Uptake of the materials from the gastrointestinal tract seems to follow the same pattern as inhalation translocation, whereas the dermal uptake of NMs is generally reported to be low. The toxicological effects in secondary organs include oxidative stress, inflammation, cytotoxicity and dysfunction of cellular and physiological processes. For toxicological and risk evaluation, further information on the toxicokinetics and persistence of NMs is crucial. The overall aim of this review is to outline the data currently available in the literature on the biokinetics, accumulation, toxicity and eventual fate of NMs in order to assess the potential risks posed by NMs to secondary organs.

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Section: Discussionmentioning

confidence: 97%

Nanomaterial translocation–the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs–a review

Kermanizadeh

Balharry

Wallin

et al. 2015

Critical Reviews in Toxicology

141

View full text Add to dashboard Cite

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“…A comparison between Poloxamer 407-functionalized single-walled carbon nanotubes (PSWCNT) and Poloxamer 407 functionalized graphene nanosheets (PGNS) showed that the geometry of the carbon nanomaterial affected the cellular uptake, in vivo fate, and the efficacy of photothermal anticancer therapy. The data revealed that PGNS provided a higher cellular uptake, longer blood circulation time, preferential distribution in the tumor tissue, and higher photothermal effect [44].…”

Section: The Morphology Changes Of S Aureus Using Tem Imagesmentioning

confidence: 98%

Near infrared (NIR) laser mediated surface activation of graphene oxide nanoflakes for efficient antibacterial, antifungal and wound healing treatment

Khan

Abdelhamid²,

2015

Colloids and Surfaces B: Biointerfaces

180

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“…Moreover, the strong NIR absorbance also makes SWNTs a robust photothermal agent for photothermal therapy (PTT) of cancer 9, 10, 14, 15. In order to use CNTs for applications in biomedicine, their surface functionalization is critically important in regulating their behaviors in biological systems such as toxicity (non-functionalized raw CNTs could have toxic effects), pharmacokinetic profiles, and tumor targeting capability 8, 9, 16. To date, a number of functionalization methods have been developed including covalent surface chemistry, non-covalent coating with amphiphilic molecules or polymers, or shelling with inorganic nanostructures such as mesoporous silica or gold shell 9, 17, 18.…”

Section: Introductionmentioning

confidence: 99%

Polydopamine Coated Single-Walled Carbon Nanotubes as a Versatile Platform with Radionuclide Labeling for Multimodal Tumor Imaging and Therapy

Zhao¹,

Chao²,

Liu³

et al. 2016

Theranostics

117

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Single-walled carbon nanotubes (SWNTs) with various unique properties have attracted great attention in cancer theranostics. Herein, SWNTs are coated with a shell of polydopamine (PDA), which is further modified by polyethylene glycol (PEG). The PDA shell in the obtained SWNT@PDA-PEG could chelate Mn2+, which together with metallic nanoparticulate impurities anchored on SWNTs offer enhanced both T1 and T2 contrasts under magnetic resonance (MR) imaging. Meanwhile, also utilizing the PDA shell, radionuclide 131I could be easily labeled onto SWNT@PDA-PEG, enabling nuclear imaging and radioisotope cancer therapy. As revealed by MR & gamma imaging, efficient tumor accumulation of SWNT@PDA-131I-PEG is observed after systemic administration into mice. By further utilizing the strong near-infarared (NIR) absorbance of SWNTs, NIR-triggered photothermal therapy in combination with 131I-based radioisotope therapy is realized in our animal experiments, in which a remarkable synergistic antitumor therapeutic effect is observed compared to monotherapies. Our work not only presents a new type of theranostic nanoplatform based on SWNTs, but also suggests the promise of PDA coating as a general approach to modify nano-agents and endow them with highly integrated functionalities.

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Structure-dependent photothermal anticancer effects of carbon-based photoresponsive nanomaterials

Cited by 60 publications

References 30 publications

Nanomaterial translocation–the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs–a review

Nanomaterial translocation–the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs–a review

Near infrared (NIR) laser mediated surface activation of graphene oxide nanoflakes for efficient antibacterial, antifungal and wound healing treatment

Polydopamine Coated Single-Walled Carbon Nanotubes as a Versatile Platform with Radionuclide Labeling for Multimodal Tumor Imaging and Therapy

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