Structure of deoxycrustecdysone, a second crustacean moulting hormone

Endocrine Control of Reproduction in Decapod Crustacea

“…The Y-organs and prothoracic glands are presumed to be the sources of the moulting hormones which are a group of steroids, collectively called ecdysones, effective in diverse classes of arthropods (Schneiderman & Krishnakumaran, 1968). In crustaceans, M H may comprise different molecules like crustecdysone (20-hydroxyecdysone) (Hampshire & Horn, 1966) and the deoxycrustecdysone (Galbraith, Horn, Middleton & Hackney, 1968). M H is primarily responsible for initiating premoult, but it also influences other functions like the hardening of the cuticle (Faux, Horn, Middleton, Fales & Lowe, 1969), colour change (Adiyodi & Adiyodi, 1969), regeneration (Passano, 1960; R. G. and gonad maturation.…”

Induction of abalone larval metamorphosis by thyroid hormones

“…Among the metamorphosis‐related hormones, 20‐hydroxyecdysone did not induce a significantly greater number of larvae to metamorphose than the negative controls (Fig. 1), even though it is well known as a moulting hormone in insects 7 and crustaceans 8,9 . However, T4 was a potent inducer of abalone metamorphosis.…”

“…1), even though it is well known as a moulting hormone in insects 7 and crustaceans. 8,9 However, T4 was a potent inducer of abalone metamorphosis. Haliotis discus discus metamorphosed strongly in response to T4 at concentrations of 1 µg/well and 10 µg/well (0.38 mM…”

Chemistry of Natural Products Derived from Marine Sources

“…Work of HORN and co-workers (98,II4,IJ4,268) led to the isolation and characterization of crustacean moulting hormones: crustecdysone (5) and deoxycrustecdysone (6) lalandei. The crustacean moulting hormones are highly active in the Calliphora test, normally used for insect moulting hormones (9I, I57, I58).…”