Structure of fish serum albumins

Андреева, А. М.

doi:10.1134/s0022093010020018

Cited by 44 publications

(35 citation statements)

References 33 publications

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“…When peripheral lipids are mobilized in mammals, free fatty acids are initially transported to the liver by albumin (75). Although previous research has reported that albumin is absent in eel serum (49,52), it is possible that, as in other fish, other fatty acid-binding proteins, such as palmitate-binding proteins, could take on this task (2,17,67). If this is, indeed, the case, then Lpl and Apoe will not be required by the liver to access the fats released from peripheral depots during fasting, prompting the reduction in their synthesis.…”

Section: R939mentioning

confidence: 98%

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

Damsteegt

Falahatimarvast

McCormick

et al. 2015

American Journal of Physiology-Regulatory, Integrative and Comp

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During certain stages in an animal's life cycle, energy requirements may exceed energy intake from the diet. The spawning migration of temperate eels is a textbook example of negative energy balance, forcing these fish to rely on stored fats (triacylglycerides) to provide their muscles with energy for swimming and their growing oocytes with the nutrients needed to develop and support healthy offspring. We predicted broad implications of this great need for endogenous triacylglycerides in terms of their packaging, transport, and ovarian uptake. To test this, serum lipid concentrations and transcript abundances of intestinal and hepatic triacylglyceride packagers and ovarian triacylglyceride modifiers and receivers were investigated throughout previtellogenesis (feeding phase) and into early vitellogenesis (fasting phase) in short-finned eels. A switch from exogenous to endogenous triacylglyceride packaging was seen as the liver upregulated transcript levels of apolipoprotein B and microsomal triacylglyceride transport protein and downregulated those of apolipoprotein E and lipoprotein lipase. In the intestine, the reverse response was observed. Furthermore, ovarian transcript abundances of triacylglyceride modifiers and receivers increased (apolipoprotein E, lipoprotein lipase, and vitellogenin receptor), indicative of increased triacylglyceride uptake during previtellogenesis. We propose that increased hepatic apolipoprotein B production is a conserved vertebrate response to prolonged periods of negative energy balance.

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Section: R939mentioning

confidence: 98%

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

Damsteegt

Falahatimarvast

McCormick

et al. 2015

American Journal of Physiology-Regulatory, Integrative and Comp

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“…Identification of albumin in teleost fish is difficult, due to the atypical location of the protein on electropherograms [20]. Salmonid species contain a protein with a molecular weight of 66 kDa, while in the common carp Cyprinus carpio, no equivalent albumin-like protein has been identified [21].…”

Section: Plasma Proteins and 1d-age Fractionationmentioning

confidence: 99%

Effects of waterborne Cu exposure in gilthead sea bream (Sparus aurata): A proteomic approach

Isani

Andreani

Carpenè

et al. 2011

Fish & Shellfish Immunology

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“…This may be due to the fact that albumin is not essential for the maintenance of oncotic pressure in some fish species, and other proteins, such as the lipid-binding apolipoproteins, can function as the main transport proteins in its absence [18] . In general, lower levels of albumin/albumin-like proteins are observed in salt water fish compared to fresh water species, however, there are large knowledge gaps concerning the albumin/albumin-like proteins of lower vertebrates [ 19 , 20 ]. Detection of albumins in Teleost fish have been reported as a difficult task due to the great variability of their characteristics and the low homology between different fish species and between mammalian and fish [ 19 , 20 ].…”

Section: Resultsmentioning

confidence: 99%

Identification of an albumin-like protein in plasma of Atlantic cod ( Gadus morhua ) and its biomarker potential for PAH contamination

Enerstvedt

Sydnes

Pampanin

2017

Heliyon

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Increased research efforts are currently focusing on Atlantic cod (Gadus morhua) and its significance for monitoring the contaminant situation in marine environments. Polycyclic aromatic hydrocarbons (PAHs) are well known toxic and carcinogenic compounds, thus continuous monitoring is required to ensure ecosystem sustainability and human food safety. A sensitive biomarker of PAH exposure in humans is the detection of PAH metabolites bound to albumin in blood. The potential of a similar PAH-albumin biomarker in Atlantic cod was therefore investigated by a desktop bioinformatic study followed by liquid chromatography mass spectrometry/mass spectrometry analysis of plasma from 16 fish. For the first time, an albumin-like protein in plasma of Atlantic cod is described, and the biomarker potential based on PAH-albumin adduct detection is discussed. Due to the detected low abundance of the albumin-like protein, it was found unlikely to be applicable as a new biomarker tool for evaluation of PAH exposure.

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Structure of fish serum albumins

Cited by 44 publications

References 33 publications

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

Effects of waterborne Cu exposure in gilthead sea bream (Sparus aurata): A proteomic approach

Identification of an albumin-like protein in plasma of Atlantic cod ( Gadus morhua ) and its biomarker potential for PAH contamination

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