Full-size and miniature Large Hadron Collider (LHC) detectors fabricated on 4-and 6-in wafers have been processed using oxygenated and nonoxygenated substrates. After irradiation to 3 10 14 cm 2 with 24-GeV/c protons and short-term annealing, these detectors have been studied in terms of their charge collection as a function of depletion voltage with LHC-speed analog electronics. Results are presented indicating the degree of improvement seen in terms of the main operationally significant parameter, namely, the bias voltage needed for a given signal read out with fast electronics.