Studies on acquired resistance of the cotton rat against microfilariae ofLitomosoides carinii

Analysis of Infection Characteristics and Antiparasite Immune Responses in Resistant Compared with Susceptible Hosts

“…& Copeman, D.B., unpublished observation). In another filarial system, uterine mf have been shown to be more potent immunogens than peripheral mf (Wegerhof & Wenk 1979). Clearly, the next stage in this project is to isolate uterine mf surface antigens recognized differentially by sera from infected versus mf-injected cattle and to test for activity in inducing host-protective (perhaps transmission-blocking) immunity under circumstances of natural or artificial exposure to the insect vector.…”