Studies on adjuvanticity of sodium houttuyfonate and its mechanism

The Constituents and Their Bioactivities of Houttuynia cordata

“…35) Vero cells (3.5ϫ10 5 /dish) were overlaid with test compounds (100 mM) and 100 plaque forming units (PFU) of HSV-1 were added to each dish. The viruses were adsorbed for 1 h at 37°C and 1% methylcellulose was added to each well.…”

“…2) Besides, the whole plant has also been reported to have the antileukemic activity, 3) anticancer activity, 4) adjuvanticity, 5) antioxidant action, 6) and inhibitory effects on anaphylactic reaction and mast cell activation.…”

Kinetics of Renin Inhibition by Sodium Houttuyfonate Analogs

“…14) Using the molecular structure of sodium houttuyfonate as a starting point, a series of analogs were synthesized by elongation of the hydrocarbon side chain. The analogs were found to have antibacterial, immunological enhancement and lysozyme function modulating activities both in vitro and in vivo [15][16][17][18] but the ability of SHAs to modulate RAS has never been reported. The aim of the present work was to determine the in vitro inhibitory activity and mode of action of SHAs against renin, a potential target for the action of therapeutic agents against cardiovascular disorders.…”

Design, Synthesis and Biological Evaluation of 3-(4-Halophenyl)-3-oxopropanal and Their Derivatives as Novel Antibacterial Agents

“…7) Recently studies have showed that Houttuyfonate homologues (HOU-Cn) derived from Houttuynin could improve the immune ability of mice and inhibit the growth of Staphylococcus aureus and Bacillus subtilis efficiently. 8) In addition, it was worthy noted that, sodium houttuyfonate ( Fig. 1), the addition compound of sodium bisulfite and Houttuynin, has been used as an antimicrobial medicine in clinical practice because of better activity and lower side effect than Houttuynin.…”