Studies on correlations among parasitaemia and some hemolytic indices in two tropical diseases (theileriosis and anaplasmosis) in Fars province of Iran

Abstract

This study was carried out in two observational clinical studies. Study 1 comprised 50 adult crossbred cattle naturally infected by Theileria annulata. Infected animals were divided into 4 subgroups with different parasitaemia (<1%, 1-3%, 3-5% and >5%). Study 2 comprised 20 adult crossbred cattle naturally infected by Anaplasma marginale. Infected animals were divided into 3 subgroups with different parasitaemia (<10%, 10-20% and 20-30%). In study 1, a significant negative correlation (P<0.001) was observed between parasitaemia and superoxide dismutase (SOD). Positive correlations (P<0.001) were observed between parasitaemia and lactate dehydrogenase (LDH) and mean corpuscular fragility (MCF). In study 2 positive correlations (P<0.05) were observed among parasitaemia and MCF and LDH activity. SOD activity had a negative correlation with parasitaemia in cattle with parasitaemia lower than 10% but no significant correlation (P>0.05) was observed between SOD activity and parasitaemia in cattle with 10-20 and 20-30% parasitaemia. In comparison of both studies we came to the conclusion that in theileriosis as the severity of disease increased the anaemia, MCF and LDH activity increased and SOD activity decreased at any parasitaemia, but in anaplasmosis the anaemia, MCF and LDH activity increased at any parasitaemia but SOD activity decreased only in early but not in advanced stages of disease.

Effect of age and gender on some blood biochemical parameters of apparently healthy small ruminants from Southern Punjab in Pakistan

“…Increased activity of LDH is probably due to vascular thrombosis, hemorrhage and tissue breakdown especially in liver and kidney of infected animals [21] . The value of LDH is higher in case of sheep (583.8暲83.6) than those of goats (304.2暲143.0) and this difference is statistically highly significant (P=0.001).…”

Correlations Among the Level of Homocysteine, Antioxidant Enzymes, Antioxidant Vitamins and Lipid Peroxidation of Erythrocytes in Malignant Ovine Theileriosis

“…Also, despite previous studies on bovine tropical theileriosis pointing out an immune-mediated hemolysis indicated by the presence of a hemagglutinin in T. annulata infected calves (Hooshmand-Rad, 1976), some recent findings suggest that anemia could be a consequence of the oxidative damage of RBCs, as well as significant modulation of erythrocytic antioxidant enzymes activities (Shiono et al, 2003;Rezaei and Dalir-Naghadeh, 2006;Nazifi et al, 2008). On the other hand, other studies have suggested that erythrocyte destruction during oxidative stress was related to lipid peroxidation of the RBCs (Friedman, 1979;Grewal et al, 2005).…”

Prevalencia de parásitos hematrópicos endoglobulares en bovinos gyr puros en Córdoba, Colombia

“…Al examen clínico se evidencia depresión, debilidad, pérdida de peso, ictericia, fiebre y anemia progresiva, disminución en la producción de leche y muerte (16). Los animales que se recuperan de este curso clínico o poseen preinmunidad permanecen infectados sin manifestaciones clínicas, y sirven como reservorio del microorganismo (20).…”