Studies on design of customized orthopedic endoprostheses of titanium alloy manufactured by SLM

Leordean, Dan; Radu, Sever Adrian; Frăţilă, Domnita; Berce, Petru

doi:10.1007/s00170-015-6873-0

Cited by 20 publications

(17 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This can be attributed to the reduced ratio of temperature gradient to solidification rate, as well as the increased turbulence of melt pools [75] . Increased laser intensity appears to increase density and therefore reduce porosity [76,77] . The increased laser intensity, while creating a larger immediate melt pool, also affects previous layers, resulting in increased heating/cooling cycles -this allows for microstructural refinement in much the same way as increased scan rates.…”

Section: Slm Part Propertiesmentioning

confidence: 99%

Additive Manufacturing of Titanium Alloys for Orthopedic Applications: A Materials Science Viewpoint

et al. 2018

View full text Add to dashboard Cite

Titanium‐based orthopedic implants are increasingly being fabricated using additive manufacturing (AM) processes such as selective laser melting (SLM), direct laser deposition (DLD), and electron beam melting (EBM). These techniques have the potential to not only produce implants with properties comparable to conventionally manufactured implants, but also improve on standard implant models. These models can be customized for individual patients using medical data, and design features, such as latticing, hierarchical scaffolds, or features to complement patient anatomy, can be added using AM to produce highly functional patient‐anatomy‐specific implants. Alloying prospects made possible through AM allow for the production of Ti‐based parts with compositions designed to reduce modulus and stress shielding while improving bone fixation and formation. The design‐to‐process lead time can be drastically shortened using AM and associated post‐processing, making possible the production of tailored implants for individual patients. This review examines the process and product characteristics of the three major metallic AM techniques and assesses the potential for these in the increased global uptake of AM in orthopedic implant fabrication.

show abstract

Section: Slm Part Propertiesmentioning

confidence: 99%

Additive Manufacturing of Titanium Alloys for Orthopedic Applications: A Materials Science Viewpoint

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The main advantages of 3D-printed custom implants are significant reduction in operative time, precise matching, quality assurance and improved biofunctionality. 21 With the implantation of prosthesis, the natural anatomy of the pelvis is to be restored by matching the prosthesis design to the patient's pelvis. Due to the complexity of pelvic bone and its fixation system, studies on the effectiveness of fixations and biomechanics of pelvic bone are rare.…”

Section: Introductionmentioning

confidence: 99%

Development of finite element model for customized prostheses design for patient with pelvic bone tumor

Iqbal

Shi

Wang

et al. 2017

Proc Inst Mech Eng H

View full text Add to dashboard Cite

The aim of this study was to design a hemi-pelvic prosthesis for a patient affected by pelvic sarcoma. To investigate the biomechanical functionality of the pelvis reconstructed with designed custom-made prosthesis, a patient-specific finite element model of whole pelvis with primary ligaments inclusive was constructed based on the computed tomography images of the patient. Then, a finite element analysis was performed to calculate and compare the stress distribution between the normal and implanted pelvis models when undergoing three different static conditions-both-leg standing, single-leg standing for the healthy and the affected one. No significant differences were observed in the stresses between the normal and reconstructed pelvis for both-leg standing, but 20%-40% larger stresses were predicted for the peak stress of the single-leg standing (affected side). Moreover, two- to threefold of peak stresses were predicted within the prostheses compared to that of the normal pelvis especially for single-leg standing case, however, still below the allowable fatigue limitation. The study on the load transmission functionality of prosthesis indicated that it is crucial to carry out finite element analysis for functional evaluation of the designed customized prostheses before three-dimensional printing manufacturing, allowing better understanding of the possible peak stresses within the bone as well as the implants for safety precaution. The finite element model can be equally applicable to other bone tumor model for biomechanical studying.

show abstract

“…The Young's modulus of a single crystalline beta-type Ti-15Mo-5Zr-3Al alloy has an anisotropic Young's modulus; the lowest Young's modulus is very close to that of bone along the specific crystallographic direction [34]. In addition, SLM can provide implants adapted to the bone shape of each patient [35], as in the present.…”

Section: Plos Onementioning

confidence: 51%

Impaired bone quality characterized by apatite orientation under stress shielding following fixing of a fracture of the radius with a 3D printed Ti-6Al-4V custom-made bone plate in dogs

et al. 2020

View full text Add to dashboard Cite

Custom-made implants have recently gained attention in veterinary medicine because of their ability to properly fit animal bones having a wide variety of shapes and sizes. The effect of custom-made implants on bone soundness and the regeneration process is not yet clear. We fabricated a 3D printed Ti-6Al-4V custom-made bone plate that fits the shape of the dog radius, and placed it into the radius where an osteotomy had been made. The preferential orientation of the apatite c-axis contributes to the mechanical integrity of the bone and is a reliable measure of bone quality. We determined this parameter as well as the bone shape and bone mineral density (BMD). The bone portion which lies parallel to the bone plate exhibited bone resorption, decreased BMD, and significant degradation of apatite orientation, relative to the portion outside the plate, at 7 months after the operation. This demonstrates the presence of stress shielding in which applied stress is not transmitted to bone due to the insertion of a stiff bone plate. This reduced stress condition clearly influences the bone regeneration process. The apatite orientation in the regenerated site remained different even after 7 months of regeneration, indicating insufficient mechanical function in the regenerated portion. This is the first study in which the apatite orientation and BMD of the radius were evaluated under conditions of stress shielding in dogs. Our results suggest that assessment of bone repair by radiography can indicate the degree of restoration of BMD, but not the apatite orientation.

show abstract

Studies on design of customized orthopedic endoprostheses of titanium alloy manufactured by SLM

Cited by 20 publications

References 13 publications

Additive Manufacturing of Titanium Alloys for Orthopedic Applications: A Materials Science Viewpoint

Additive Manufacturing of Titanium Alloys for Orthopedic Applications: A Materials Science Viewpoint

Development of finite element model for customized prostheses design for patient with pelvic bone tumor

Impaired bone quality characterized by apatite orientation under stress shielding following fixing of a fracture of the radius with a 3D printed Ti-6Al-4V custom-made bone plate in dogs

Contact Info

Product

Resources

About