Studies on imprint smears of the ovarian tumors of common epithelial origin.

Identification of intranuclear inclusions is useful for the cytological diagnosis of ovarian clear cell carcinoma

“…Some characteristic cytological features of each ovarian carcinoma subtype have already been described: formation of psammoma bodies and papillary or micropapillary clusters in SC; endometrial carcinoma‐like morphology and squamous differentiation in EC; tall columnar cells containing intracytoplasmic mucin with background mucin in MC; and abundant clear cytoplasm, hobnail cells, and hyalinized material in CCC . Nishino and Khunamornpong et al reported that the diagnostic accuracy of ovarian carcinoma subtyping by imprint cytology was 47.4% and 61.5%, respectively. With regard to CCC, Nishino reported that discrimination between CCC and MC is difficult when tumor cells show a honeycomb appearance with clear cytoplasm.…”

“…Nishino and Khunamornpong et al reported that the diagnostic accuracy of ovarian carcinoma subtyping by imprint cytology was 47.4% and 61.5%, respectively. With regard to CCC, Nishino reported that discrimination between CCC and MC is difficult when tumor cells show a honeycomb appearance with clear cytoplasm. Thus, ovarian carcinoma subtyping using cytological specimens is occasionally difficult due to overlapping cytological features of each subtype.…”