Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats

Effect of Retinol Feeding on Liver Cholesterol of Rats

“…Studies in hypo-and hypervitaminotic A rats have implicated the role of vitamin A in isoprene metabolism (1)(2)(3)(4)(5)(6)(7)(8)(9). Deficiency of vitamin A reduced the incorporation of acetate-1-14C, and mevalonate-2-14C into liver cholesterol, whereas excess of vitamin A caused an increased incorporation of acetate-1-14C and meva lonate-2-14C into liver cholesterol (1,2,8).…”