Studies on perioperative skin flora

Evaluation of Surgical Scrub Methods for Large Animal Surgeons

“…'* Chlorhexidine has been reported to have a residual effect on skin flora for 6 hours and perhaps as long as 3 days. 13 The wide range of colony counts for the prescrub sample in the clean trials was attributed to unusually high colony counts associated with one individual. Colony counts for this individual were consistently higher for the prescrub sample for all eight procedures.…”

Local Chemolysis of Obstructive Uric Acid Stone with 0.1 <i>M</i> THAM and 0.02% Chlorhexidine

“…Thus, the side effects of pyrexia, urinary tract infection and septicemia are not infrequently encoun tered. Because chlorhexidine had exhibited antibacterial activity [7][8][9] and been safely used in urinary bladder instillation to control urinary tract infection [12][13][14], it was used in the present study as an additive in order to prevent urinary tract infection. Truly, compared with our previous study [3], this form of therapy significantly reduced the incidence of pyrexia and urinary tract infec tion.…”

“…On the other hand, chlorhexidine can effectively inhibit Escherichia coli, Klebsiella spp. and Staphylococ cus epidermidis [7][8][9]. Thus, in order to improve the ther apeutic effect and reduce the complications of local che molysis, we used a modified chemolytic formula by com bining THAM with chlorhexidine to treat obstructive uric acid stones.…”

Searching for Evidence Regarding Using Preoperative Disinfection Showers to Prevent Surgical Site Infections: A Systematic Review

“…Chlorhexidine gluconate (CHG) used in antiseptic sponges is a skin disinfection product, which reduces the risk of microbial contamination. CHG attaches to the skin and has a prolonged effect, which can be an advantage during long‐lasting surgery (Lowbury et al 1974; Ayliffe et al 1988; Newsom et al 1988; Mangram et al 1999; Edmiston et al 2007). It has been demonstrated that the numbers of bacteria do not return until five days after disinfection with CHG (Lilly et al 1979).…”

“…It has been demonstrated that the numbers of bacteria do not return until five days after disinfection with CHG (Lilly et al 1979). By then, the surgical incision is normally healed (Newsom & Rowland 1988; Lindholm 2003). Further, it has been shown that CHG has a cumulative effect if used repeatedly, and Lilly et al (1979) showed a 99% reduction of the skin flora after five hand disinfections with CHG. Then there was a sharp rise in the numbers of bacteria, which was explained as bacteria present in deeper skin‐layers being brought to the surface by the massaging effects of hand washing (Lilly et al 1979).…”