STUDIES ON THE ANALYSIS AND CHEMISTRY OF NEOARSPHENAMINE¹

Urinary Oxalate Excretion by Man Following Ascorbic Acid Ingestion.

“…It is of interest to note that Dominguez, Corcoran and Page ( 4 ) in evaluating the use of mannitol in renal function concluded from their studies that the utilization of mannitol in humans, although small after IV injection, is presumably metabolic. It is of interest to note that Dominguez, Corcoran and Page ( 4 ) in evaluating the use of mannitol in renal function concluded from their studies that the utilization of mannitol in humans, although small after IV injection, is presumably metabolic.…”

“…With intraperitoneal injection, the mannitol is largely recovered in Oxalic acid has long been known to be a product of the in vitro oxidation of ascorbic acid (1)(2)(3)(4)(5). Radioactive mannitol has been administered to rats with the following results: 1.…”

Studies on the Analysis and Chemistry of Neoarsphenamine II. Studies on the Chemistry of Sodium Formalde-Hydesulphoxylate and their Relation to the Structure of Neoarsphenamine**Scientific Section, A.PH.A., Rapid City meeting, 1929.

“…Previous results (1) have shown that two distinct types of "sulphoxylate" derivative might be formed in this reaction, namely, the N methylene substitution product and the double salt form. It is the former type with which this discussion is concerned, and in order to obtain some information regarding the nature of the linkage between the amino group of the arsphenamine nucleus and the sodium formaldehydesulphoxylate, it was necessary to obtain information concerning the structure of sodium formaldehydesulphoxylate.…”