2005
DOI: 10.1016/j.jep.2005.01.017
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Studies on the antihypertensive, antispasmodic, bronchodilator and hepatoprotective activities of the Carum copticum seed extract

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Cited by 154 publications
(104 citation statements)
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“…Moringa oleifera, known to be rich in multiple medicinally active chemicals, may be a good candidate to see if it contains effect enhancing and/or side-effects neutralizing combinations. Medicinal plants are relatively rich in their contents of calcium channel blockers (CCBs) which are known to possess a wide variety of pharmacological activities such as antihypertensive, hepatoprotective, antiulcer, antiasthmatic, antispasmodic and antidiarroeal (Stephens and Rahwan, 1992;Gilani et al, 1994b;2005b;Yaeesh et al, 2006; and it remains to be seen whether such activities reported to be present in Moringa oleifera have a direct link with the presence of CCBs.…”
Section: Future Prospectsmentioning
confidence: 99%
“…Moringa oleifera, known to be rich in multiple medicinally active chemicals, may be a good candidate to see if it contains effect enhancing and/or side-effects neutralizing combinations. Medicinal plants are relatively rich in their contents of calcium channel blockers (CCBs) which are known to possess a wide variety of pharmacological activities such as antihypertensive, hepatoprotective, antiulcer, antiasthmatic, antispasmodic and antidiarroeal (Stephens and Rahwan, 1992;Gilani et al, 1994b;2005b;Yaeesh et al, 2006; and it remains to be seen whether such activities reported to be present in Moringa oleifera have a direct link with the presence of CCBs.…”
Section: Future Prospectsmentioning
confidence: 99%
“…9 Adult rats (180-200 g) of either sex were used. The animals were anesthetized with an intraperitoneal (i.p.)…”
Section: Pharmacological Parametersmentioning
confidence: 99%
“…Direct vasodilator activity and its possible mode of action were studied using isolated rabbit aortae as described by Gilani et al 9 For the in vitro study, we preferred to use rabbits that are commonly used in our laboratory for different purposes, thus using multiple tissues from the same animals to maximize ethical and economical utilization. Rabbits were killed by cervical dislocation.…”
Section: Pharmacological Parametersmentioning
confidence: 99%
“…The identification of these family of compounds further supports claims of the use of this plants as a traditional medicine as these compounds have valuable amoebicidal, antifugal and anti-inflammatory properties 12,13 . They have stimulating and tnifying effects on the muscles when consumed and this probably accounts for their use in enhancing male potency.…”
Section: Resultsmentioning
confidence: 62%